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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH44391.1PP-loop domain protein; COGs: COG0037 ATPase of the PP-loop superfamily protein implicated in cell cycle control; InterPro IPR011063:IPR012089; KEGG: saf:SULAZ_1054 PP-loop domain protein; PFAM: PP-loop domain protein; SPTR: PP-loop domain protein; IMG reference gene:2505283803; PFAM: PP-loop family; TIGRFAM: TIGR00269 family protein; Belongs to the TtcA family. (302 aa)    
Predicted Functional Partners:
AEH45421.1
tRNA methyltransferase complex GCD14 subunit; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
 
  
 0.812
AEH44392.1
Ribonuclease BN; COGs: COG1295 membrane protein; InterPro IPR017039:IPR004664:IPR000944; KEGG: ade:Adeh_0697 ribonuclease BN, putative; PFAM: ribonuclease BN; protein of unknown function UPF0074; SPTR: Ribonuclease BN, putative; TIGRFAM: ribonuclease BN; IMG reference gene:2505283804; PFAM: Ribonuclease BN-like family; Transcriptional regulator; TIGRFAM: YihY family protein (not ribonuclease BN).
       0.791
AEH44393.1
Type IV pilus secretin PilQ; COGs: COG4796 Type II secretory pathway component HofQ; InterPro IPR013355:IPR011662:IPR004846:IPR001775; KEGG: pfo:Pfl01_0409 type II and III secretion system protein; PFAM: type II and III secretion system protein; Secretin/TonB short domain; SPTR: Pilus secretin; TIGRFAM: type IV pilus secretin PilQ; IMG reference gene:2505283805; PFAM: Bacterial type II/III secretion system short domain; Secretin and TonB N terminus short domain; Bacterial type II and III secretion system protein; TIGRFAM: type IV pilus secretin (or competence protein) PilQ.
 
     0.688
AEH44394.1
KEGG: mxa:MXAN_5773 putative lipoprotein; SPTR: Fimbrial assembly protein; IMG reference gene:2505283806; PFAM: Pilus assembly protein, PilP.
       0.631
AEH44395.1
Hypothetical protein; KEGG: dak:DaAHT2_2311 pilus assembly protein PilO; SPTR: Pilus assembly protein PilO; IMG reference gene:2505283807; PFAM: Pilus assembly protein, PilO.
       0.631
AEH44396.1
InterPro IPR007813; KEGG: dol:Dole_0332 fimbrial assembly family protein; PFAM: Fimbrial assembly family protein; SPTR: Fimbrial assembly family protein; IMG reference gene:2505283808; PFAM: Fimbrial assembly protein (PilN).
       0.631
AEH44397.1
COGs: COG4972 Tfp pilus assembly protein ATPase PilM; KEGG: dol:Dole_0333 type IV pilus assembly protein PilM; SPTR: Type IV pilus assembly protein PilM; IMG reference gene:2505283809; PFAM: Competence protein A; TIGRFAM: type IV pilus assembly protein PilM.
       0.631
hisH
Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF; Belongs to the HisA/HisF family.
  
 
 0.576
cysS
Cysteine synthase; COGs: COG0215 Cysteinyl-tRNA synthetase; InterProIPR001926:IPR015803:IPR001216:IPR005856:IPR 002308; KEGG: sat:SYN_00075 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Cysteinyl-tRNA synthetase; TIGRFAM: cysteine synthase; cysteinyl-tRNA synthetase; IMG reference gene:2505283966; PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthases; cysteinyl-tRNA synthetase; cysteine synthase B.
     
 0.534
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
     
 0.528
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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