Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH44396.1InterPro IPR007813; KEGG: dol:Dole_0332 fimbrial assembly family protein; PFAM: Fimbrial assembly family protein; SPTR: Fimbrial assembly family protein; IMG reference gene:2505283808; PFAM: Fimbrial assembly protein (PilN). (178 aa)    
Predicted Functional Partners:
AEH44397.1
COGs: COG4972 Tfp pilus assembly protein ATPase PilM; KEGG: dol:Dole_0333 type IV pilus assembly protein PilM; SPTR: Type IV pilus assembly protein PilM; IMG reference gene:2505283809; PFAM: Competence protein A; TIGRFAM: type IV pilus assembly protein PilM.
 
 
 0.982
AEH44395.1
Hypothetical protein; KEGG: dak:DaAHT2_2311 pilus assembly protein PilO; SPTR: Pilus assembly protein PilO; IMG reference gene:2505283807; PFAM: Pilus assembly protein, PilO.
 
 
 0.973
AEH44393.1
Type IV pilus secretin PilQ; COGs: COG4796 Type II secretory pathway component HofQ; InterPro IPR013355:IPR011662:IPR004846:IPR001775; KEGG: pfo:Pfl01_0409 type II and III secretion system protein; PFAM: type II and III secretion system protein; Secretin/TonB short domain; SPTR: Pilus secretin; TIGRFAM: type IV pilus secretin PilQ; IMG reference gene:2505283805; PFAM: Bacterial type II/III secretion system short domain; Secretin and TonB N terminus short domain; Bacterial type II and III secretion system protein; TIGRFAM: type IV pilus secretin (or competence protein) PilQ.
 
 
 0.961
AEH44394.1
KEGG: mxa:MXAN_5773 putative lipoprotein; SPTR: Fimbrial assembly protein; IMG reference gene:2505283806; PFAM: Pilus assembly protein, PilP.
  
  
 0.938
AEH44392.1
Ribonuclease BN; COGs: COG1295 membrane protein; InterPro IPR017039:IPR004664:IPR000944; KEGG: ade:Adeh_0697 ribonuclease BN, putative; PFAM: ribonuclease BN; protein of unknown function UPF0074; SPTR: Ribonuclease BN, putative; TIGRFAM: ribonuclease BN; IMG reference gene:2505283804; PFAM: Ribonuclease BN-like family; Transcriptional regulator; TIGRFAM: YihY family protein (not ribonuclease BN).
 
     0.673
AEH44391.1
PP-loop domain protein; COGs: COG0037 ATPase of the PP-loop superfamily protein implicated in cell cycle control; InterPro IPR011063:IPR012089; KEGG: saf:SULAZ_1054 PP-loop domain protein; PFAM: PP-loop domain protein; SPTR: PP-loop domain protein; IMG reference gene:2505283803; PFAM: PP-loop family; TIGRFAM: TIGR00269 family protein; Belongs to the TtcA family.
       0.631
AEH44012.1
RimK domain protein ATP-grasp; COGs: COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); InterPro IPR013651:IPR011761; KEGG: dak:DaAHT2_2245 RimK domain protein ATP-grasp; PFAM: RimK domain protein ATP-grasp; SPTR: RimK domain protein ATP-grasp; IMG reference gene:2505283410; PFAM: RimK-like ATP-grasp domain.
  
     0.596
AEH44399.1
COGs: COG0681 Signal peptidase I; InterProIPR000223:IPR019759:IPR019756:IPR019757:IPR 019758; KEGG: tye:THEYE_A0098 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; PRIAM: Signal peptidase I; SPTR: Signal peptidase I; TIGRFAM: signal peptidase I; IMG reference gene:2505283811; PFAM: Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type.
       0.553
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
       0.535
AEH44049.1
KEGG: pca:Pcar_3121 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505283447.
  
     0.515
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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