Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
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AEH44401.1Diguanylate cyclase; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: dde:Dde_1584 response regulator receiver modulated diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; SPTR: GGDEF; TIGRFAM: diguanylate cyclase; IMG reference gene:2505283813; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. (307 aa)    
Predicted Functional Partners:
AEH44846.1
Diguanylate cyclase/phosphodiesterase with GAF sensor; COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterPro IPR000160:IPR001633:IPR003018; KEGG: rfr:Rfer_1825 response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: EAL domain protein; GGDEF domain containing protein; GAF domain protein; SMART: EAL domain protein; GGDEF domain containing protein; SPTR: Response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S); TIGRFAM: diguanylate cyclase; IMG [...]
 
 
 0.868
AEH44403.1
KEGG: dak:DaAHT2_0260 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505283815.
 
     0.867
AEH44402.1
Metal dependent phosphohydrolase; COGs: COG1639 signal transduction protein; InterPro IPR006675:IPR013976:IPR003607; KEGG: dak:DaAHT2_0261 metal dependent phosphohydrolase; PFAM: Metal-dependent hydrolase HDOD; SMART: metal-dependent phosphohydrolase HD region; SPTR: Metal-dependent phosphohydrolase, HD subdomain; TIGRFAM: metal dependent phophohydrolase; IMG reference gene:2505283814; PFAM: HDOD domain; TIGRFAM: uncharacterized domain HDIG.
 
     0.828
gatA
glutamyl-tRNA(Gln) amidotransferase, A subunit; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).
       0.789
gatC
glutamyl-tRNA(Gln) amidotransferase, C subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.
   
   0.787
AEH44406.1
Phosphomethylpyrimidine kinase; COGs: COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; InterPro IPR004399:IPR013749:IPR019293; KEGG: pho:PH1155 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; Phosphomethylpyrimidine kinase; PRIAM: Phosphomethylpyrimidine kinase; SPTR: 446aa long hypothetical thiamine biosynthesis protein; TIGRFAM: phosphomethylpyrimidine kinase; IMG reference gene:2505283818; PFAM: Phosphomethylpyrimidine kinase; Archaeal phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase.
       0.753
AEH44155.1
Diguanylate cyclase; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: sde:Sde_1595 response regulator receiver domain-containing protein; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; SPTR: GGDEF domain; TIGRFAM: diguanylate cyclase; IMG reference gene:2505283556; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
     0.731
AEH44225.1
Diguanylate cyclase; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: tdn:Suden_1570 diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; SPTR: Diguanylate cyclase (GGDEF domain); TIGRFAM: diguanylate cyclase; IMG reference gene:2505283631; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
  
     0.730
AEH45526.1
Metal dependent phosphohydrolase; COGs: COG2206 HD-GYP domain; InterPro IPR003607:IPR006674; KEGG: dvm:DvMF_0995 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Metal dependent phosphohydrolase; IMG reference gene:2505284989; PFAM: HD domain.
 
 
 0.724
AEH45443.1
Response regulator receiver modulated metal dependent phosphohydrolase; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR006675:IPR001789:IPR003607:IPR006674; KEGG: dat:HRM2_37390 predicted two-component system transcriptional regulator; PFAM: response regulator receiver; metal-dependent phosphohydrolase HD sub domain; SMART: response regulator receiver; metal-dependent phosphohydrolase HD region; SPTR: Predicted two-component system transcriptional regulator; TIGRFAM: metal dependent phophohydrolase; IMG reference gene:250528490 [...]
  
  
 0.530
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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