Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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[Homology]
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AEH44441.1Haloacid dehalogenase domain protein hydrolase; COGs: COG0546 phosphatase; InterPro IPR005834:IPR005833; KEGG: dak:DaAHT2_2039 HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: HAD-superfamily hydrolase, subfamily IA, variant 3; IMG reference gene:2505283854; PFAM: haloacid dehalogenase-like hydrolase. (216 aa)    
Predicted Functional Partners:
AEH43888.1
FAD linked oxidase domain protein; COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094:IPR004113:IPR016166:IPR020904; KEGG: sfu:Sfum_0534 FAD linked oxidase domain-containing protein; PFAM: FAD linked oxidase domain protein; SPTR: FAD linked oxidase domain protein; manually curated; IMG reference gene:2505283283; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD.
    
 0.911
AEH45876.1
FAD linked oxidase domain protein; COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094:IPR004113:IPR016166; KEGG: tye:THEYE_A0668 glycolate oxidase subunit; PFAM: FAD linked oxidase domain protein; SPTR: Glycolate oxidase subunit; IMG reference gene:2505285362; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD.
    
 0.911
AEH43989.1
COGs: COG0247 Fe-S oxidoreductase; InterPro IPR004017:IPR017896:IPR017900; KEGG: drt:Dret_1037 protein of unknown function DUF224 cysteine-rich region domain protein; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505283386; PFAM: Cysteine-rich domain.
    
 0.902
AEH45875.1
CoB--CoM heterodisulfide reductase; COGs: COG0247 Fe-S oxidoreductase; InterPro IPR012257:IPR017900:IPR004017:IPR017896; KEGG: tye:THEYE_A0667 iron-sulfur cluster-binding protein; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; PRIAM: CoB--CoM heterodisulfide reductase; SPTR: Iron-sulfur cluster-binding protein; IMG reference gene:2505285361; PFAM: Cysteine-rich domain.
    
 0.902
AEH44439.1
Polyprenyl synthetase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: sfu:Sfum_1586 trans-hexaprenyltranstransferase; PFAM: Polyprenyl synthetase; SPTR: Trans-hexaprenyltranstransferase; IMG reference gene:2505283852; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
       0.798
AEH44440.1
Extracellular ligand-binding receptor; COGs: COG0683 ABC-type branched-chain amino acid transport systems periplasmic component; InterPro IPR001828:IPR000709; KEGG: dvm:DvMF_1478 extracellular ligand-binding receptor; PFAM: Extracellular ligand-binding receptor; SPTR: Extracellular ligand-binding receptor; IMG reference gene:2505283853; PFAM: Receptor family ligand binding region.
   
   0.782
AEH44442.1
KEGG: rms:RMA_0544 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505283855.
       0.773
AEH44443.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660:IPR003661:IPR003594:IPR004358:IPR 005467; KEGG: sus:Acid_7874 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SPTR: Integral membrane sensor signal transduction histidine kinase; IMG reference gene:2505283856; PFAM: HAMP domain; Histidine kinase-, DN [...]
       0.762
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
  
 0.597
argG
COGs: COG0137 Argininosuccinate synthase; InterPro IPR001518:IPR018223; KEGG: dak:DaAHT2_2212 argininosuccinate synthase; PFAM: argininosuccinate synthase; PRIAM: Argininosuccinate synthase; SPTR: Argininosuccinate synthase; TIGRFAM: argininosuccinate synthase; IMG reference gene:2505283851; PFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
     
 0.596
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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