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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
crcBCrcB protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. (125 aa)    
Predicted Functional Partners:
AEH44447.1
Protein of unknown function DUF190; COGs: COG1993 conserved hypothetical protein; InterPro IPR003793; KEGG: ddf:DEFDS_0610 hypothetical protein; PFAM: protein of unknown function DUF190; SPTR: Putative uncharacterized protein; IMG reference gene:2505283860; PFAM: Uncharacterized ACR, COG1993.
 
   
 0.952
AEH44449.1
Glycosyl transferase family 39; COGs: COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family; InterPro IPR003342; KEGG: tye:THEYE_A0589 hypothetical protein; PFAM: glycosyl transferase family 39; SPTR: Putative uncharacterized protein; IMG reference gene:2505283862; PFAM: Dolichyl-phosphate-mannose-protein mannosyltransferase.
  
    0.780
AEH44450.1
Phosphoesterase PA-phosphatase related protein; InterPro IPR000326; KEGG: min:Minf_1458 membrane-associated phospholipid phosphatase; PFAM: phosphoesterase PA-phosphatase related; SMART: phosphoesterase PA-phosphatase related; SPTR: Membrane-associated phospholipid phosphatase; IMG reference gene:2505283863; PFAM: PAP2 superfamily.
       0.779
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
      
 0.444
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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