close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH44471.1Amino acid-binding ACT domain protein; InterPro IPR002912; KEGG: mem:Memar_1825 beta-lactamase domain-containing protein; PFAM: amino acid-binding ACT domain protein; SPTR: Beta-lactamase domain protein; IMG reference gene:2505283885; PFAM: Metallo-beta-lactamase superfamily; ACT domain. (505 aa)    
Predicted Functional Partners:
AEH44959.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR002355:IPR001763:IPR013027:IPR004099; KEGG: dps:DP2890 NADH oxidase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SMART: Rhodanese domain protein; SPTR: Related to NADH oxidase; IMG reference gene:2505284398; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Rhodanese-like domain; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain.
  
 0.827
AEH45853.1
Hypothetical protein; InterPro IPR018391; KEGG: dal:Dalk_4066 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505285336.
 
   0.691
AEH45750.1
Metallophosphoesterase; COGs: COG0420 DNA repair exonuclease; InterPro IPR004843; KEGG: mta:Moth_1789 metallophosphoesterase; PFAM: metallophosphoesterase; SPTR: Exonuclease SbcD; IMG reference gene:2505285226; PFAM: Calcineurin-like phosphoesterase.
 
     0.668
AEH45854.1
COGs: COG0619 ABC-type cobalt transport system permease component CbiQ and related transporter; InterPro IPR003339; KEGG: dal:Dalk_4068 cobalt transport protein; PFAM: cobalt transport protein; SPTR: Cobalt transport protein; IMG reference gene:2505285337; PFAM: Cobalt transport protein.
  
    0.655
AEH45749.1
Glycosyltransferase 28 domain protein; COGs: COG0419 ATPase involved in DNA repair; InterPro IPR007235; KEGG: mif:Metin_0813 SMC domain protein; PFAM: Glycosyltransferase 28 domain; SPTR: DNA double-strand break repair Rad50 ATPase; IMG reference gene:2505285225.
  
    0.602
AEH44468.1
COGs: COG2812 DNA polymerase III gamma/tau subunits; InterPro IPR004622; KEGG: pca:Pcar_1692 DNA polymerase III, gamma/tau subunits; SPTR: DNA polymerase III, delta prime subunit; TIGRFAM: DNA polymerase III, delta prime subunit; IMG reference gene:2505283882; TIGRFAM: DNA polymerase III, delta' subunit.
  
   0.593
ybeY
Pyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. Belongs to the endoribonuclease YbeY family.
  
 
 0.580
AEH45662.1
Hypothetical protein; InterPro IPR019734:IPR013026; KEGG: dak:DaAHT2_1194 tetratricopeptide TPR_4; SPTR: Tetratricopeptide TPR_4; IMG reference gene:2505285133.
  
     0.570
murA
UDP-N-acetylglucosamine1- carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
       0.557
prmC
protein-(glutamine-N5) methyltransferase, release factor-specific; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
       0.557
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.