Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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[Homology]
Score
AEH44473.1Alpha,alpha-trehalose-phosphate synthase (UDP-forming); COGs: COG0380 Trehalose-6-phosphate synthase; InterPro IPR012766:IPR003337:IPR006379:IPR001830; KEGG: mem:Memar_2216 putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; PFAM: glycosyl transferase family 20; trehalose-phosphatase; SPTR: Alpha,alpha-trehalose-phosphate synthase (UDP-forming); TIGRFAM: alpha,alpha-trehalose-phosphate synthase [UDP-forming]; trehalose-phosphatase; HAD-superfamily hydrolase, subfamily IIB; IMG reference gene:2505283887; PFAM: Trehalose-phosphatase; Glycosyltransferase fami [...] (726 aa)    
Predicted Functional Partners:
AEH44475.1
COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: sfu:Sfum_2348 glycosyl transferase, group 1; PFAM: glycosyl transferase group 1; SPTR: Glycosyl transferase, group 1; IMG reference gene:2505283889; PFAM: Glycosyl transferases group 1.
 0.990
AEH45988.1
UTP-glucose-1-phosphate uridylyltransferase; COGs: COG1210 UDP-glucose pyrophosphorylase; InterPro IPR005835:IPR005771; KEGG: dak:DaAHT2_0367 UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase; PRIAM: UTP--glucose-1-phosphate uridylyltransferase; SPTR: UTP-glucose-1-phosphate uridylyltransferase; TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; IMG reference gene:2505285477; PFAM: Nucleotidyl transferase; TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase.
    
 0.955
AEH44474.1
KEGG: pca:Pcar_3110 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505283888.
 
 
 0.930
AEH45952.1
Aminoglycoside phosphotransferase; COGs: COG2187 conserved hypothetical protein; InterPro IPR002575; KEGG: tye:THEYE_A1962 Uma3; PFAM: aminoglycoside phosphotransferase; SPTR: Uma3; IMG reference gene:2505285441; PFAM: Chromatin associated protein KTI12.
   
    0.924
AEH44969.1
Nucleotidyl transferase; COGs: COG0448 ADP-glucose pyrophosphorylase; InterPro IPR005836:IPR018103:IPR005835; KEGG: dak:DaAHT2_1367 nucleotidyl transferase; PFAM: Nucleotidyl transferase; SPTR: Glucose-1-phosphate adenylyltransferase; IMG reference gene:2505284408; PFAM: Nucleotidyl transferase; TIGRFAM: glucose-1-phosphate adenylyltransferase; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
     
 0.873
AEH45041.1
Nucleotidyl transferase; COGs: COG0448 ADP-glucose pyrophosphorylase; InterPro IPR005836:IPR005835; KEGG: dak:DaAHT2_1368 nucleotidyl transferase; PFAM: Nucleotidyl transferase; SPTR: Nucleotidyl transferase; IMG reference gene:2505284484; PFAM: Nucleotidyl transferase; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
     
 0.873
AEH45085.1
NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR008089:IPR001509; KEGG: ckr:CKR_1837 hypothetical protein; PFAM: NAD-dependent epimerase/dehydratase; SPTR: Putative uncharacterized protein; IMG reference gene:2505284530; PFAM: NAD dependent epimerase/dehydratase family.
     
 0.801
AEH45268.1
COGs: COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog; InterPro IPR000394:IPR007046:IPR007634; KEGG: sat:SYN_00945 RNA polymerase sigma-54 factor; PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; sigma-54 factor; SPTR: RNA polymerase sigma-54 factor; TIGRFAM: RNA polymerase sigma-54 factor, RpoN; IMG reference gene:2505284717; PFAM: Sigma-54 factor, Activator interacting domain (AID); Sigma-54, DNA binding domain; Sigma-54 factor, core binding domain; TIGRFAM: RNA polymerase sigma-54 factor.
   
    0.736
aspS
aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
       0.694
AEH44364.1
Transketolase domain-containing protein; COGs: COG0021 Transketolase; InterPro IPR005474:IPR005475:IPR005476; KEGG: sfu:Sfum_1302 transketolase; PFAM: Transketolase domain-containing protein; Transketolase central region; SPTR: Transketolase domain protein; IMG reference gene:2505283771; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain.
   
  
 0.667
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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