Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lolDABC transporter related protein; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. (238 aa)    
Predicted Functional Partners:
AEH44486.1
Lipoprotein releasing system, transmembrane protein, LolC/E family; COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR011925:IPR003838; KEGG: sfu:Sfum_3743 LolC/E family lipoprotein releasing system, transmembrane protein; PFAM: protein of unknown function DUF214; SPTR: Lipoprotein releasing system, transmembrane protein, LolC/E family; TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family; IMG reference gene:2505283900; PFAM: Predicted permease; TIGRFAM: lipoprotein releasing system, transmembrane protein, Lol [...]
 
 0.996
lysS
COGs: COG1190 Lysyl-tRNA synthetase (class II); InterProIPR002313:IPR006195:IPR004365:IPR004364:IPR 018149; KEGG: sfu:Sfum_3742 lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; SPTR: Lysyl-tRNA synthetase; TIGRFAM: lysyl-tRNA synthetase; IMG reference gene:2505283901; PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: lysyl-tRNA synthetase, eukaryotic and non-spirochete bacterial; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
     0.855
AEH44484.1
COGs: COG4775 Outer membrane protein/protective antigen OMA87; InterPro IPR016474:IPR010827:IPR000184; KEGG: dak:DaAHT2_1309 outer membrane protein assembly complex, YaeT protein; PFAM: surface antigen (D15); surface antigen variable number repeat-containing protein; SPTR: Surface antigen (D15):Surface antigen variable number; TIGRFAM: outer membrane protein assembly complex, YaeT protein; IMG reference gene:2505283898; PFAM: Surface antigen variable number repeat; Surface antigen; TIGRFAM: outer membrane protein assembly complex, YaeT protein.
     
 0.837
AEH44483.1
Auxin Efflux Carrier; COGs: COG0679 permease; InterPro IPR004776; KEGG: dak:DaAHT2_2426 auxin efflux carrier; PFAM: Auxin Efflux Carrier; SPTR: Auxin Efflux Carrier; IMG reference gene:2505283897; PFAM: Membrane transport protein.
       0.655
AEH44488.1
UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR014016:IPR000212; KEGG: drt:Dret_2402 UvrD/REP helicase; PFAM: UvrD/REP helicase; SPTR: UvrD/REP helicase; IMG reference gene:2505283902; PFAM: UvrD/REP helicase.
  
    0.583
tsaD
Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
 
    0.573
AEH44670.1
COGs: COG2834 Outer membrane lipoprotein-sorting protein; InterPro IPR018323:IPR004564; KEGG: dak:DaAHT2_0277 outer membrane lipoprotein carrier protein LolA; PFAM: outer membrane lipoprotein carrier protein LolA; SPTR: Outer membrane lipoprotein carrier protein LolA; TIGRFAM: outer membrane lipoprotein carrier protein LolA; IMG reference gene:2505284089; PFAM: Outer membrane lipoprotein carrier protein LolA; TIGRFAM: periplasmic chaperone LolA.
   
 
 0.527
rpsE
Ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.
  
   
 0.527
AEH45405.1
KEGG: dba:Dbac_2225 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505284863; PFAM: Protein of unknown function (DUF1329).
   
 
 0.527
rsmA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
 
 
 
 0.511
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.