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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH44489.1Metal dependent phosphohydrolase; COGs: COG1639 signal transduction protein; InterPro IPR013976:IPR003607; KEGG: dal:Dalk_3268 metal dependent phosphohydrolase; PFAM: Metal-dependent hydrolase HDOD; SMART: metal-dependent phosphohydrolase HD region; SPTR: Metal dependent phosphohydrolase; IMG reference gene:2505283903; PFAM: HDOD domain; TIGRFAM: uncharacterized domain HDIG. (305 aa)    
Predicted Functional Partners:
AEH44789.1
COGs: COG1639 signal transduction protein; InterPro IPR013976; KEGG: dar:Daro_1602 protein kinase:GAF; PFAM: Metal-dependent hydrolase HDOD; SPTR: Protein kinase:GAF; IMG reference gene:2505284220; PFAM: HDOD domain.
  
     0.771
AEH46063.1
COGs: COG1639 signal transduction protein; InterPro IPR013976; KEGG: slt:Slit_2006 serine/threonine protein kinase; PFAM: Metal-dependent hydrolase HDOD; SPTR: Serine/threonine protein kinase; IMG reference gene:2505285554; PFAM: HDOD domain.
  
     0.751
AEH44490.1
COGs: COG5483 conserved hypothetical protein; InterPro IPR014519; KEGG: tye:THEYE_A0530 hypothetical protein; SPTR: Conserved Archaeal protein; IMG reference gene:2505283904; PFAM: Protein of unknown function, DUF488.
       0.631
AEH44488.1
UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR014016:IPR000212; KEGG: drt:Dret_2402 UvrD/REP helicase; PFAM: UvrD/REP helicase; SPTR: UvrD/REP helicase; IMG reference gene:2505283902; PFAM: UvrD/REP helicase.
       0.618
fliE
COGs: COG1677 Flagellar hook-basal body protein; InterPro IPR001624; KEGG: tme:Tmel_1126 flagellar hook-basal body complex subunit FliE; PFAM: flagellar hook-basal body complex protein FliE; SPTR: Flagellar hook-basal body complex subunit FliE; TIGRFAM: flagellar hook-basal body complex subunit FliE; IMG reference gene:2505285137; PFAM: Flagellar hook-basal body complex protein FliE; TIGRFAM: flagellar hook-basal body complex protein FliE.
  
    0.496
AEH45669.1
Flagellar assembly protein FliH/Type III secretion system HrpE; COGs: COG1317 Flagellar biosynthesis/type III secretory pathway protein; InterPro IPR018035; KEGG: dal:Dalk_0669 flagellar assembly protein FliH; PFAM: Flagellar assembly protein FliH/Type III secretion system HrpE; SPTR: Flagellar assembly protein FliH; IMG reference gene:2505285140; PFAM: Flagellar assembly protein FliH.
  
     0.480
AEH44484.1
COGs: COG4775 Outer membrane protein/protective antigen OMA87; InterPro IPR016474:IPR010827:IPR000184; KEGG: dak:DaAHT2_1309 outer membrane protein assembly complex, YaeT protein; PFAM: surface antigen (D15); surface antigen variable number repeat-containing protein; SPTR: Surface antigen (D15):Surface antigen variable number; TIGRFAM: outer membrane protein assembly complex, YaeT protein; IMG reference gene:2505283898; PFAM: Surface antigen variable number repeat; Surface antigen; TIGRFAM: outer membrane protein assembly complex, YaeT protein.
       0.468
lolD
ABC transporter related protein; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
       0.468
AEH44486.1
Lipoprotein releasing system, transmembrane protein, LolC/E family; COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR011925:IPR003838; KEGG: sfu:Sfum_3743 LolC/E family lipoprotein releasing system, transmembrane protein; PFAM: protein of unknown function DUF214; SPTR: Lipoprotein releasing system, transmembrane protein, LolC/E family; TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family; IMG reference gene:2505283900; PFAM: Predicted permease; TIGRFAM: lipoprotein releasing system, transmembrane protein, Lol [...]
       0.468
lysS
COGs: COG1190 Lysyl-tRNA synthetase (class II); InterProIPR002313:IPR006195:IPR004365:IPR004364:IPR 018149; KEGG: sfu:Sfum_3742 lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; SPTR: Lysyl-tRNA synthetase; TIGRFAM: lysyl-tRNA synthetase; IMG reference gene:2505283901; PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: lysyl-tRNA synthetase, eukaryotic and non-spirochete bacterial; Belongs to the class-II aminoacyl-tRNA synthetase family.
       0.468
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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