Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH44521.1KEGG: srm:SRM_00767 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505283936; PFAM: Protein of unknown function (DUF2281). (69 aa)    
Predicted Functional Partners:
AEH44520.1
KEGG: rca:Rcas_0617 transcriptional modulator of MazE/toxin, MazF; SPTR: Transcriptional modulator of MazE/toxin, MazF; IMG reference gene:2505283935; PFAM: PemK-like protein.
       0.799
AEH44522.1
KEGG: sfu:Sfum_0165 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505283937.
       0.456
AEH44523.1
Uncharacterized protein family UPF0102; COGs: COG0792 endonuclease distantly related to Holliday junction resolvase; InterPro IPR003509; KEGG: dak:DaAHT2_1166 protein of unknown function UPF0102; PFAM: Uncharacterised protein family UPF0102; SPTR: Putative uncharacterized protein; IMG reference gene:2505283938; PFAM: Uncharacterised protein family UPF0102; TIGRFAM: TIGR00252 family protein; Belongs to the UPF0102 family.
       0.456
rnhB
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
       0.456
rplS
Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
       0.456
AEH44526.1
Protein of unknown function DUF2168; COGs: COG4752 conserved hypothetical protein; InterPro IPR019230; KEGG: tjr:TherJR_2045 protein of unknown function DUF2168; PFAM: Protein of unknown function DUF2168; SPTR: Putative uncharacterized protein; IMG reference gene:2505283941; PFAM: Uncharacterized protein conserved in bacteria (DUF2168).
       0.435
trmD
tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
       0.435
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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