Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH44523.1Uncharacterized protein family UPF0102; COGs: COG0792 endonuclease distantly related to Holliday junction resolvase; InterPro IPR003509; KEGG: dak:DaAHT2_1166 protein of unknown function UPF0102; PFAM: Uncharacterised protein family UPF0102; SPTR: Putative uncharacterized protein; IMG reference gene:2505283938; PFAM: Uncharacterised protein family UPF0102; TIGRFAM: TIGR00252 family protein; Belongs to the UPF0102 family. (115 aa)    
Predicted Functional Partners:
rplS
Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
   
   0.818
AEH44522.1
KEGG: sfu:Sfum_0165 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505283937.
       0.806
rnhB
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
       0.806
trmD
tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
 
     0.792
AEH45149.1
Mg chelatase, subunit ChlI; COGs: COG0606 ATPase with chaperone activity; InterPro IPR004482:IPR003593:IPR000523:IPR001208; KEGG: dal:Dalk_5279 Mg chelatase, subunit ChlI; PFAM: magnesium chelatase ChlI subunit; SMART: AAA ATPase; SPTR: Mg chelatase, subunit ChlI; TIGRFAM: Mg chelatase, subunit ChlI; IMG reference gene:2505284596; PFAM: Magnesium chelatase, subunit ChlI; TIGRFAM: Mg chelatase-related protein.
 
    0.781
AEH44526.1
Protein of unknown function DUF2168; COGs: COG4752 conserved hypothetical protein; InterPro IPR019230; KEGG: tjr:TherJR_2045 protein of unknown function DUF2168; PFAM: Protein of unknown function DUF2168; SPTR: Putative uncharacterized protein; IMG reference gene:2505283941; PFAM: Uncharacterized protein conserved in bacteria (DUF2168).
       0.763
AEH44895.1
COGs: COG1040 amidophosphoribosyltransferase; InterPro IPR000836; KEGG: cth:Cthe_2248 phosphoribosyltransferase; PFAM: phosphoribosyltransferase; SPTR: Phosphoribosyltransferase; IMG reference gene:2505284334; PFAM: Phosphoribosyl transferase domain; TIGRFAM: comF family protein.
 
    0.699
AEH45445.1
DNA protecting protein DprA; COGs: COG0758 Rossmann fold nucleotide-binding protein involved in DNA uptake; InterPro IPR003488; KEGG: gme:Gmet_0890 smf protein; PFAM: SMF family protein; SPTR: SMF protein; TIGRFAM: DNA protecting protein DprA; IMG reference gene:2505284906; PFAM: DNA recombination-mediator protein A; TIGRFAM: DNA protecting protein DprA.
 
  
 0.610
uppP
Undecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
       0.527
ruvC
Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
 
     0.520
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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