close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH44543.1Protein of unknown function DUF111; COGs: COG1641 conserved hypothetical protein; InterPro IPR002822; KEGG: dth:DICTH_1434 hypothetical protein; PFAM: protein of unknown function DUF111; SPTR: UPF0272 protein DICTH_1434; IMG reference gene:2505283959; PFAM: Protein of unknown function DUF111; TIGRFAM: TIGR00299 family protein; Belongs to the LarC family. (390 aa)    
Predicted Functional Partners:
AEH45221.1
Asparagine synthase; COGs: COG1606 ATP-utilizing protein of the PP-loop superfamily; InterPro IPR005232:IPR001962; KEGG: ate:Athe_1202 PP-loop domain protein; PFAM: asparagine synthase; SPTR: PP-loop domain protein; IMG reference gene:2505284668; PFAM: Asparagine synthase; TIGRFAM: TIGR00268 family protein.
 
 0.960
AEH43930.1
1-(5-phosphoribosyl)-5-amino-4-imidazole- carboxylate (AIR) carboxylase; COGs: COG1691 NCAIR mutase (PurE)-related protein; InterPro IPR000031; KEGG: dal:Dalk_0112 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; SPTR: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; IMG reference gene:2505283327; PFAM: AIR carboxylase.
 
  
 0.915
AEH44544.1
SNARE associated Golgi protein-like protein; COGs: COG0398 conserved hypothetical protein; InterPro IPR015414; KEGG: dal:Dalk_0616 SNARE associated Golgi protein; PFAM: SNARE associated Golgi protein; SPTR: SNARE associated Golgi protein; IMG reference gene:2505283960; PFAM: SNARE associated Golgi protein.
       0.791
AEH44545.1
COGs: COG0226 ABC-type phosphate transport system periplasmic component; InterPro IPR006059:IPR005673; KEGG: dge:Dgeo_0649 periplasmic phosphate binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: ABC-type phosphate transport system, periplasmic component, PstS; TIGRFAM: phosphate ABC transporter, periplasmic phosphate-binding protein; IMG reference gene:2505283961; PFAM: Bacterial extracellular solute-binding protein; TIGRFAM: phosphate ABC transporter, phosphate-binding protein; Belongs to the PstS family.
       0.563
AEH44880.1
Cobalamin (vitamin B12) biosynthesis CbiM protein; COGs: COG0310 ABC-type Co2+ transport system permease component; InterPro IPR002751; KEGG: dsa:Desal_0774 cobalt transport protein CbiM; PFAM: cobalamin (vitamin B12) biosynthesis CbiM protein; SPTR: Cobalamin (Vitamin B12) biosynthesis CbiM protein; IMG reference gene:2505284318; PFAM: Cobalt uptake substrate-specific transmembrane region; TIGRFAM: cobalamin biosynthesis protein CbiM.
  
    0.457
AEH45161.1
COGs: COG2768 Uncharacterized Fe-S center protein; InterPro IPR017900:IPR017896; KEGG: dol:Dole_2297 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein; IMG reference gene:2505284608; PFAM: 4Fe-4S binding domain.
 
    0.425
AEH44546.1
Hypothetical protein; InterPro IPR011031; KEGG: sse:Ssed_4024 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated; selenocysteine-containing protein; IMG reference gene:2505283962.
       0.414
AEH44547.1
InterPro IPR005797; KEGG: nmr:Nmar_1543 cytochrome b/b6 domain-containing protein; PFAM: Cytochrome b/b6 domain; SPTR: Cytochrome b/b6 domain; IMG reference gene:2505283963.
       0.409
AEH44548.1
Rieske (2Fe-2S) iron-sulfur domain protein; COGs: COG0723 Rieske Fe-S protein; InterPro IPR017941:IPR005805; KEGG: sth:STH3146 plastoquinol--plastocyanin reductase; PFAM: Rieske [2Fe-2S] iron-sulphur domain; SPTR: Plastoquinol--plastocyanin reductase; IMG reference gene:2505283964; PFAM: Rieske [2Fe-2S] domain.
       0.409
AEH44549.1
RNA methyltransferase, TrmA family; COGs: COG2265 SAM-dependent methyltransferase related to tRNA (uracil-5-)-methyltransferase; InterPro IPR002792:IPR010280:IPR001566; KEGG: gem:GM21_2158 RNA methyltransferase, TrmA family; PFAM: (Uracil-5)-methyltransferase; deoxyribonuclease/rho motif-related TRAM; SPTR: RNA methyltransferase, TrmA family; TIGRFAM: RNA methyltransferase, TrmA family; IMG reference gene:2505283965; PFAM: TRAM domain; tRNA (Uracil-5-)-methyltransferase; TIGRFAM: 23S rRNA (uracil-5-)-methyltransferase RumA; Belongs to the class I-like SAM-binding methyltransferase supe [...]
       0.409
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.