close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH44606.1dTDP-glucose 4,6-dehydratase; COGs: COG1088 dTDP-D-glucose 4 6-dehydratase; InterPro IPR001509:IPR005888; KEGG: saf:SULAZ_0364 dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: dTDP-glucose 4,6-dehydratase; TIGRFAM: dTDP-glucose 4,6-dehydratase; IMG reference gene:2505284023; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (331 aa)    
Predicted Functional Partners:
AEH44607.1
dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
 
 0.999
AEH44609.1
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
 
 
 0.999
AEH44605.1
dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.
 
 
0.991
AEH44967.1
Bifunctional GlmU protein; COGs: COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains); InterPro IPR001451; KEGG: dps:DP2923 bifunctional GlmU protein; SPTR: Probable bifunctional GlmU protein; IMG reference gene:2505284406.
    
 0.916
AEH45078.1
Nucleotide sugar dehydrogenase; COGs: COG1004 UDP-glucose 6-dehydrogenase; InterPro IPR001732:IPR014026:IPR014027:IPR017476; KEGG: ddf:DEFDS_0115 UDP-glucose 6-dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; PRIAM: UDP-glucose 6-dehydrogenase; SPTR: UDP-glucose 6-dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; IMG reference gene:2505284523; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP- [...]
 
  
 0.874
AEH45611.1
NAD-dependent epimerase/dehydratase; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR001509; KEGG: mno:Mnod_5601 oxidoreductase domain protein; PFAM: NAD-dependent epimerase/dehydratase; oxidoreductase domain protein; SPTR: Oxidoreductase domain protein; IMG reference gene:2505285078; PFAM: NAD dependent epimerase/dehydratase family; Oxidoreductase family, NAD-binding Rossmann fold.
 
  
0.870
AEH44614.1
Polysaccharide biosynthesis protein; InterPro IPR002797; KEGG: clj:CLJU_c05530 putative polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein; SPTR: Polysaccharide biosynthesis protein; IMG reference gene:2505284031; PFAM: Polysaccharide biosynthesis protein.
  
  
 0.857
AEH44616.1
N-acylneuraminate cytidylyltransferase; COGs: COG1083 CMP-N-acetylneuraminic acid synthetase; InterPro IPR003329; KEGG: mru:mru_1876 CMP-N-acetylneuraminic acid synthetase NeuA; PFAM: acylneuraminate cytidylyltransferase; PRIAM: N-acylneuraminate cytidylyltransferase; SPTR: CMP-N-acetylneuraminic acid synthetase NeuA; IMG reference gene:2505284033; PFAM: Cytidylyltransferase; Glycosyltransferase family 28 C-terminal domain.
  
  
 0.854
AEH45614.1
KEGG: pdi:BDI_2788 putative lipopolysaccharide biosynthesis protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505285082; PFAM: Polysaccharide biosynthesis protein.
  
  
 0.762
AEH44328.1
UDP-4-keto-6-deoxy-N-acetylglucosamine 4-aminotransferase; COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR020026:IPR000653; KEGG: msi:Msm_1536 pleiotropic regulatory protein DegT (PLP-dependent); PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: DegT/DnrJ/EryC1/StrS aminotransferase; TIGRFAM: UDP-4-keto-6-deoxy-N-acetylglucosamine 4-aminotransferase; IMG reference gene:2505283735; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; TIGRFAM: UDP-4-keto-6-deoxy-N-acetylglucosamine 4-aminotransferase; Belongs to t [...]
 
  
 0.665
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
Server load: low (38%) [HD]