Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH44642.1COGs: COG0517 FOG: CBS domain; InterPro IPR000644; KEGG: dvl:Dvul_0535 CBS domain-containing protein; PFAM: CBS domain containing protein; SMART: CBS domain containing protein; SPTR: CBS domain protein/ACT domain protein; IMG reference gene:2505284061; PFAM: CBS domain. (238 aa)    
Predicted Functional Partners:
proS
prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...]
       0.597
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.586
AEH44641.1
COGs: COG1189 rRNA methylase; InterPro IPR002942:IPR002877:IPR004538; KEGG: gme:Gmet_1222 hemolysin A; PFAM: ribosomal RNA methyltransferase RrmJ/FtsJ; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; SPTR: Hemolysin A; TIGRFAM: hemolysin A; IMG reference gene:2505284060; PFAM: S4 domain; FtsJ-like methyltransferase; TIGRFAM: hemolysin TlyA family protein.
  
    0.582
AEH45762.1
COGs: COG0123 Deacetylase including yeast histone deacetylase and acetoin utilization protein; InterPro IPR000286:IPR003084; KEGG: sat:SYN_00740 histone deacetylase family protein; PFAM: histone deacetylase superfamily; SPTR: Histone deacetylase family protein; IMG reference gene:2505285238; PFAM: Histone deacetylase domain.
  
    0.469
AEH45871.1
COGs: COG0123 Deacetylase including yeast histone deacetylase and acetoin utilization protein; InterPro IPR000286; KEGG: dps:DP2831 hypothetical protein; PFAM: histone deacetylase superfamily; SPTR: Putative uncharacterized protein; IMG reference gene:2505285357; PFAM: Histone deacetylase domain.
  
    0.469
folE2
GTP cyclohydrolase I; Converts GTP to 7,8-dihydroneopterin triphosphate.
       0.405
AEH44639.1
Cobyrinic acid ac-diamide synthase; COGs: COG3640 CO dehydrogenase maturation factor; InterPro IPR014433; KEGG: dak:DaAHT2_0979 cobyrinic acid ac-diamide synthase; SPTR: Cobyrinic acid a,c-diamide synthase; IMG reference gene:2505284058; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain.
       0.405
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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