Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH44719.1InterPro IPR003735; KEGG: cpb:Cphamn1_0277 protein of unknown function DUF156; PFAM: protein of unknown function DUF156; SPTR: Putative uncharacterized protein; IMG reference gene:2505284144; PFAM: Uncharacterised BCR, COG1937. (100 aa)    
Predicted Functional Partners:
AEH44720.1
Hypothetical protein; COGs: COG0348 Polyferredoxin; InterPro IPR017896:IPR017900; KEGG: gsu:GSU0729 iron-sulfur cluster-binding protein; SPTR: Iron-sulfur cluster-binding protein; IMG reference gene:2505284145.
       0.778
AEH45586.1
Protein of unknown function DUF399; COGs: COG3016 Uncharacterized iron-regulated protein; InterPro IPR001478:IPR014782:IPR007314; KEGG: pmx:PERMA_0605 putative peptidase M1, membrane alanine aminopeptidase; PFAM: protein of unknown function DUF399; Peptidase M1 membrane alanine aminopeptidase; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: Putative peptidase M1, membrane alanine aminopeptidase; IMG reference gene:2505285053; PFAM: Protein of unknown function, DUF399; PDZ domain (Also known as DHR or GLGF).
     
 0.543
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
       0.542
AEH44959.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR002355:IPR001763:IPR013027:IPR004099; KEGG: dps:DP2890 NADH oxidase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SMART: Rhodanese domain protein; SPTR: Related to NADH oxidase; IMG reference gene:2505284398; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Rhodanese-like domain; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain.
     
 0.437
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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