Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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AEH44726.1Secretion protein HlyD family protein; COGs: COG1566 Multidrug resistance efflux pump; InterPro IPR006143:IPR003997; KEGG: aae:aq_1060 hypothetical protein; PFAM: secretion protein HlyD family protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505284151; PFAM: HlyD family secretion protein. (378 aa)    
Predicted Functional Partners:
AEH44728.1
COGs: COG1538 Outer membrane protein; InterPro IPR003423; KEGG: sat:SYN_01010 type I secretion outer membrane protein; PFAM: outer membrane efflux protein; SPTR: Type I secretion outer membrane protein; IMG reference gene:2505284153; PFAM: Outer membrane efflux protein.
 
 
 0.968
AEH44727.1
Drug resistance transporter, EmrB/QacA subfamily; COGs: COG2814 Arabinose efflux permease; InterPro IPR011701:IPR004638; KEGG: ddf:DEFDS_0617 multidrug-efflux transporter MFS family; PFAM: major facilitator superfamily MFS_1; SPTR: Multidrug-efflux transporter, MFS family; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; IMG reference gene:2505284152; PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily.
 
 
 0.966
AEH44022.1
COGs: COG1538 Outer membrane protein; InterPro IPR003423; KEGG: gme:Gmet_3465 outer membrane efflux protein; PFAM: outer membrane efflux protein; SPTR: Outer membrane efflux protein; IMG reference gene:2505283420; PFAM: Outer membrane efflux protein.
 
 
 0.847
AEH45566.1
COGs: COG1538 Outer membrane protein; InterPro IPR010131:IPR003423; KEGG: dal:Dalk_1443 RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein; SPTR: RND efflux system, outer membrane lipoprotein, NodT family; TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; IMG reference gene:2505285033; PFAM: Outer membrane efflux protein; TIGRFAM: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family.
 
 
 0.787
AEH44764.1
Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; COGs: COG0836 Mannose-1-phosphate guanylyltransferase; InterPro IPR005835:IPR001538:IPR006375; KEGG: saf:SULAZ_0358 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type II; Nucleotidyl transferase; PRIAM: Mannose-6-phosphate isomerase; SPTR: Strongly similar to GDP-mannose pyrophosphorylase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; IMG reference gene:2505284191; PFAM: Nucleotidyl transferase; Mannose-6-phosphate isomera [...]
 
  
 0.563
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
     
 0.446
AEH44948.1
Response regulator receiver sensor hybrid histidine kinase; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR020053:IPR001789:IPR003661:IPR003594:IPR 004358:IPR005467; KEGG: cts:Ctha_2310 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SPTR: Putative Histidine kinase; IMG reference gene:2505284387; PFAM: Histidine [...]
  
  
 0.439
AEH44754.1
InterPro IPR011701; KEGG: gbm:Gbem_1224 major facilitator superfamily MFS_1; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily MFS_1; IMG reference gene:2505284181; PFAM: Bacterial protein of unknown function (DUF894).
 
 
 0.421
secF
Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
     
 0.408
AEH44021.1
Efflux transporter, RND family, MFP subunit; COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: sul:SYO3AOP1_1133 efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; SPTR: Efflux transporter, RND family, MFP subunit; TIGRFAM: efflux transporter, RND family, MFP subunit; IMG reference gene:2505283419; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
   
0.401
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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