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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH44729.1AMMECR1 domain protein; COGs: COG2078 conserved hypothetical protein; InterPro IPR002733; KEGG: sfu:Sfum_1996 AMMECR1 domain-containing protein; PFAM: AMMECR1 domain protein; SPTR: AMMECR1 domain protein; IMG reference gene:2505284154; PFAM: AMMECR1; TIGRFAM: uncharacterized protein, PH0010 family. (196 aa)    
Predicted Functional Partners:
AEH45190.1
Protein of unknown function DUF52; COGs: COG1355 dioxygenase; InterPro IPR002737; KEGG: geo:Geob_3013 protein of unknown function DUF52; PFAM: protein of unknown function DUF52; SPTR: Putative uncharacterized protein; IMG reference gene:2505284637; PFAM: Memo-like protein; Belongs to the MEMO1 family.
    0.986
AEH45768.1
Radical SAM domain protein; COGs: COG1180 Pyruvate-formate lyase-activating enzyme; InterPro IPR016431:IPR007197; KEGG: dak:DaAHT2_1232 radical SAM domain protein; PFAM: Radical SAM domain protein; SPTR: Radical SAM domain protein; IMG reference gene:2505285248; PFAM: Radical SAM superfamily.
     0.919
AEH44730.1
Disulfide bond isomerase, DsbC/G; InterPro IPR018950; KEGG: hth:HTH_1351 thiol:disulfide interchange protein; PFAM: Disulphide bond isomerase, DsbC/G-like; SPTR: Thiol:disulfide interchange protein; IMG reference gene:2505284155; PFAM: Disulfide bond isomerase protein N-terminus.
       0.801
AEH44681.1
Protein of unknown function DUF52; COGs: COG1355 dioxygenase; InterPro IPR002737; KEGG: sfu:Sfum_0075 hypothetical protein; PFAM: protein of unknown function DUF52; SPTR: Putative uncharacterized protein; IMG reference gene:2505284100; PFAM: Memo-like protein.
    0.769
AEH44496.1
Radical SAM domain protein; COGs: COG1180 Pyruvate-formate lyase-activating enzyme; InterPro IPR016431:IPR007197; KEGG: mtp:Mthe_1490 radical SAM domain-containing protein; PFAM: Radical SAM domain protein; SPTR: Radical SAM domain protein; IMG reference gene:2505283910; PFAM: Radical SAM superfamily.
 
     0.738
AEH44731.1
COGs: COG0075 Serine-pyruvate aminotransferase/ aspartate aminotransferase; InterPro IPR000192:IPR020578; KEGG: tna:CTN_1191 aspartate aminotransferase; PFAM: aminotransferase class V; SPTR: Serine--glyoxylate transaminase; IMG reference gene:2505284156; PFAM: Aminotransferase class-V.
       0.533
AEH44732.1
COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR006140:IPR002912:IPR006236; KEGG: dak:DaAHT2_0597 D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; amino acid-binding ACT domain protein; PRIAM: Phosphoglycerate dehydrogenase; SPTR: D-3-phosphoglycerate dehydrogenase; TIGRFAM: D-3-phosphoglycerate dehydrogenase; IMG reference gene:2505284157; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; ACT domain; D- [...]
       0.533
nnrE
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
   
  
 0.439
AEH44750.1
uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR000878:IPR003754:IPR003043:IPR006366; KEGG: dal:Dalk_4009 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; IMG reference gene:2505284177; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase.
       0.405
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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