STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AEH44732.1COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR006140:IPR002912:IPR006236; KEGG: dak:DaAHT2_0597 D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; amino acid-binding ACT domain protein; PRIAM: Phosphoglycerate dehydrogenase; SPTR: D-3-phosphoglycerate dehydrogenase; TIGRFAM: D-3-phosphoglycerate dehydrogenase; IMG reference gene:2505284157; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; ACT domain; D- [...] (528 aa)    
Predicted Functional Partners:
gpmI
Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
   
 
 0.904
AEH44085.1
Proposed homoserine kinase; COGs: COG3635 phosphoglycerate mutase AP superfamily; InterPro IPR019304:IPR006124:IPR013371:IPR004456; KEGG: tye:THEYE_A1682 proposed homoserine kinase; PFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; metalloenzyme domain protein; PRIAM: Phosphoglycerate mutase; SPTR: Proposed homoserine kinase; TIGRFAM: proposed homoserine kinase; phosphonopyruvate decarboxylase-related protein; IMG reference gene:2505283483; PFAM: Metalloenzyme superfamily; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; TIGRFAM: 2,3-bisphosphoglycerate-ind [...]
     
  0.900
AEH45865.1
Phosphonopyruvate decarboxylase-related protein; COGs: COG3635 phosphoglycerate mutase AP superfamily; InterPro IPR004456:IPR019304:IPR006124; KEGG: dak:DaAHT2_2657 phosphonopyruvate decarboxylase-related protein; PFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; metalloenzyme domain protein; PRIAM: Phosphoglycerate mutase; SPTR: Cofactor-independent phosphoglycerate mutase, archaeal; TIGRFAM: phosphonopyruvate decarboxylase-related protein; IMG reference gene:2505285351; PFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Metalloenzyme superfamily; TIGR [...]
     
  0.900
AEH44731.1
COGs: COG0075 Serine-pyruvate aminotransferase/ aspartate aminotransferase; InterPro IPR000192:IPR020578; KEGG: tna:CTN_1191 aspartate aminotransferase; PFAM: aminotransferase class V; SPTR: Serine--glyoxylate transaminase; IMG reference gene:2505284156; PFAM: Aminotransferase class-V.
 
  
 0.864
cysS
Cysteine synthase; COGs: COG0215 Cysteinyl-tRNA synthetase; InterProIPR001926:IPR015803:IPR001216:IPR005856:IPR 002308; KEGG: sat:SYN_00075 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Cysteinyl-tRNA synthetase; TIGRFAM: cysteine synthase; cysteinyl-tRNA synthetase; IMG reference gene:2505283966; PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthases; cysteinyl-tRNA synthetase; cysteine synthase B.
  
 
 0.609
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
  
 0.589
rplF
Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
   0.560
AEH44803.1
COGs: COG0077 Prephenate dehydratase; InterProIPR018528:IPR020822:IPR001086:IPR002912:IPR 008242:IPR002701; KEGG: dak:DaAHT2_0619 prephenate dehydratase; PFAM: prephenate dehydratase; Chorismate mutase, type II; amino acid-binding ACT domain protein; PRIAM: Prephenate dehydratase; SPTR: Prephenate dehydratase:Chorismate mutase:Amino acid-binding ACT; IMG reference gene:2505284236; PFAM: Prephenate dehydratase; ACT domain; Chorismate mutase type II.
     
 0.550
AEH44730.1
Disulfide bond isomerase, DsbC/G; InterPro IPR018950; KEGG: hth:HTH_1351 thiol:disulfide interchange protein; PFAM: Disulphide bond isomerase, DsbC/G-like; SPTR: Thiol:disulfide interchange protein; IMG reference gene:2505284155; PFAM: Disulfide bond isomerase protein N-terminus.
       0.540
AEH44137.1
COGs: COG0473 Isocitrate/isopropylmalate dehydrogenase; InterPro IPR001804:IPR019818; KEGG: tye:THEYE_A0114 3-isopropylmalate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase; PRIAM: 3-isopropylmalate dehydrogenase; SPTR: 3-isopropylmalate dehydrogenase; IMG reference gene:2505283537; PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: 3-isopropylmalate dehydrogenase.
  
  
 0.536
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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