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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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mfdTranscription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1167 aa)    
Predicted Functional Partners:
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 
 0.922
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 
 0.910
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 
 0.888
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 
 0.861
AEH44757.1
COGs: COG1426 conserved hypothetical protein; KEGG: tte:TTE1826 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505284184.
 
     0.824
recO
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
     
 0.823
AEH44755.1
Conserved hypothetical protein CHP00730; COGs: COG1611 Rossmann fold nucleotide-binding protein; InterPro IPR005269; KEGG: ddf:DEFDS_0585 hypothetical protein; PFAM: Conserved hypothetical protein CHP00730; SPTR: Putative uncharacterized protein; IMG reference gene:2505284182; PFAM: Possible lysine decarboxylase; TIGRFAM: TIGR00725 family protein; TIGR00730 family protein; Belongs to the LOG family.
       0.780
AEH44758.1
SurA domain protein; InterPro IPR000297:IPR015391; KEGG: dat:HRM2_28180 PpiD2; PFAM: SurA domain; PpiC-type peptidyl-prolyl cis-trans isomerase; SPTR: PpiD2; IMG reference gene:2505284185; PFAM: SurA N-terminal domain; PPIC-type PPIASE domain.
       0.780
AEH44191.1
Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
   
 
 0.707
AEH45570.1
ABC transporter related protein; COGs: COG0178 Excinuclease ATPase subunit; InterPro IPR003593:IPR003439:IPR017871; KEGG: tye:THEYE_A1038 excinuclease ABC, A subunit; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Excinuclease ABC, A subunit; IMG reference gene:2505285037; PFAM: ABC transporter.
   
 
 0.707
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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