Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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AEH44763.1Radical SAM domain protein; COGs: COG2896 Molybdenum cofactor biosynthesis protein; InterPro IPR007197:IPR006638:IPR000385; KEGG: afu:AF2104 hypothetical protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Putative uncharacterized protein; IMG reference gene:2505284190; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM additional 4Fe4S-binding domain. (381 aa)    
Predicted Functional Partners:
moaC
Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
  
  
 0.801
AEH44518.1
Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
 
 0.721
AEH46059.1
MoaD family protein; InterPro IPR003749:IPR010038; KEGG: pmo:Pmob_0384 MoaD family protein; PFAM: thiamineS protein; SPTR: MoaD family protein; TIGRFAM: MoaD family protein; IMG reference gene:2505285550; PFAM: ThiS family; TIGRFAM: MoaD family protein, archaeal.
 
  
 0.671
AEH45602.1
Sulfotransferase; InterPro IPR000863; KEGG: rxy:Rxyl_3105 sulfotransferase; PFAM: sulfotransferase; SPTR: Sulfotransferase; IMG reference gene:2505285069; PFAM: Sulfotransferase domain.
  
     0.609
AEH44441.1
Haloacid dehalogenase domain protein hydrolase; COGs: COG0546 phosphatase; InterPro IPR005834:IPR005833; KEGG: dak:DaAHT2_2039 HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: HAD-superfamily hydrolase, subfamily IA, variant 3; IMG reference gene:2505283854; PFAM: haloacid dehalogenase-like hydrolase.
  
    0.571
AEH45561.1
Molybdopterin biosynthesis MoaE protein; InterPro IPR003448; KEGG: tye:THEYE_A0839 molybdopterin converting factor, subunit 2; PFAM: molybdopterin biosynthesis MoaE protein; SPTR: Protein involved in biosynthesis of molybdopterin; IMG reference gene:2505285026; PFAM: MoaE protein.
 
  
 0.549
rplU
Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
     
 0.479
AEH44200.1
DNA binding domain protein, excisionase family; COGs: COG1910 Periplasmic molybdate-binding protein/domain; InterPro IPR010093:IPR000551; KEGG: dak:DaAHT2_2633 DNA binding domain protein, excisionase family; PFAM: regulatory protein MerR; SPTR: DNA binding domain protein, excisionase family; TIGRFAM: DNA binding domain protein, excisionase family; IMG reference gene:2505283605; TIGRFAM: DNA binding domain, excisionase family.
 
  
 0.451
AEH45388.1
Molybdenum cofactor synthesis domain protein; COGs: COG0521 Molybdopterin biosynthesis protein; InterPro IPR020817:IPR008284:IPR001453; KEGG: pca:Pcar_1966 molybdenum cofactor biosynthesis protein; PFAM: molybdopterin binding domain; SPTR: Molybdenum cofactor biosynthesis protein; TIGRFAM: molybdenum cofactor synthesis domain protein; IMG reference gene:2505284846; PFAM: Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain.
 
  
 0.451
rpmA
COGs: COG0211 Ribosomal protein L27; InterPro IPR001684:IPR018261; KEGG: pmx:PERMA_0052 50S ribosomal protein L27; PFAM: ribosomal protein L27; SPTR: 50S ribosomal protein L27; TIGRFAM: ribosomal protein L27; IMG reference gene:2505284188; PFAM: Ribosomal L27 protein; TIGRFAM: ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.
     
 0.449
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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