Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH44813.1COGs: COG0287 Prephenate dehydrogenase; InterPro IPR004455:IPR003099; KEGG: dal:Dalk_1765 prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; NADP oxidoreductase coenzyme F420-dependent; SPTR: Prephenate dehydrogenase; IMG reference gene:2505284246; PFAM: Prephenate dehydrogenase. (266 aa)    
Predicted Functional Partners:
AEH44803.1
COGs: COG0077 Prephenate dehydratase; InterProIPR018528:IPR020822:IPR001086:IPR002912:IPR 008242:IPR002701; KEGG: dak:DaAHT2_0619 prephenate dehydratase; PFAM: prephenate dehydratase; Chorismate mutase, type II; amino acid-binding ACT domain protein; PRIAM: Prephenate dehydratase; SPTR: Prephenate dehydratase:Chorismate mutase:Amino acid-binding ACT; IMG reference gene:2505284236; PFAM: Prephenate dehydratase; ACT domain; Chorismate mutase type II.
  
 
 0.975
hisC
COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR004839:IPR005861:IPR001917; KEGG: dak:DaAHT2_2672 histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Histidinol-phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; IMG reference gene:2505285486; PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
 
 0.967
AEH45243.1
Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839:IPR004838:IPR001176; KEGG: tye:THEYE_A0342 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Aspartate aminotransferase; IMG reference gene:2505284692; PFAM: Aminotransferase class I and II.
  
 
 0.907
AEH46060.1
Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR001176:IPR004839:IPR004838; KEGG: dak:DaAHT2_0099 aminotransferase class I and II; PFAM: aminotransferase class I and II; SPTR: Aminotransferase class I and II; IMG reference gene:2505285551; PFAM: Aminotransferase class I and II.
  
 
 0.907
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
  
 0.857
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
 
  
 0.844
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
  
 0.840
AEH44814.1
KEGG: chl:Chy400_3406 binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; IMG reference gene:2505284247.
       0.778
AEH44710.1
Aminotransferase class I and II; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR004839; KEGG: dat:HRM2_45660 putative histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; PFAM: aminotransferase class I and II; SPTR: Putative histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; IMG reference gene:2505284135; PFAM: Aminotransferase class I and II.
  
  
 0.692
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
  
  
 0.656
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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