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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH44833.1Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; COGs: COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I N-terminal domain; InterPro IPR004646; KEGG: drm:Dred_1872 fumarate hydratase; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region; PRIAM: Fumarate hydratase; SPTR: Fumarase alpha subunit; TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; IMG reference gene:2505284267; PFAM: Fumarate hydratase (Fumerase); TIGRFAM: hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha region. (277 aa)    
Predicted Functional Partners:
AEH45839.1
Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; COGs: COG1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I C-terminal domain; InterPro IPR004647; KEGG: dak:DaAHT2_1200 hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate beta region; SPTR: Fe-S type hydro-lyases tartrate/fumarate beta region; TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; IMG reference gene:2505285321; PFAM: Fumarase C-terminus; TIGRFAM: hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta region.
 
 0.998
mdh
Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 
 0.968
AEH46025.1
Formate dehydrogenase, alpha subunit; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterProIPR000759:IPR001041:IPR013027:IPR006963:IPR 006656:IPR006657:IPR018247:IPR017900:IPR006655:IPR017896:I PR006478; KEGG: dak:DaAHT2_0823 formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; ferredoxin; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; SPTR: Formate dehydrogenase, alpha subunit; TIGRFAM: formate dehydrogenase, alpha subunit; manually curated; selenocysteine- [...]
     
 0.827
argH
COGs: COG0165 Argininosuccinate lyase; InterPro IPR009049:IPR000362:IPR020557:IPR003031; KEGG: pca:Pcar_2418 argininosuccinate lyase; PFAM: fumarate lyase; SPTR: Argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; IMG reference gene:2505284614; PFAM: Lyase; TIGRFAM: argininosuccinate lyase.
    
  0.813
AEH43928.1
COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR001176:IPR004839:IPR005958:IPR004838; KEGG: aba:Acid345_1458 aminotransferase; PFAM: aminotransferase class I and II; SPTR: Aminotransferase; TIGRFAM: tyrosine/nicotianamine aminotransferase; IMG reference gene:2505283325; PFAM: Aminotransferase class I and II; TIGRFAM: tyrosine aminotransferase, eukaryotic; tyrosine/nicotianamine aminotransferases.
     
  0.800
AEH44378.1
Hypothetical protein; COGs: COG2864 Cytochrome b subunit of formate dehydrogenase; InterPro IPR000516; KEGG: slp:Slip_1532 formate dehydrogenase, putative; SPTR: Putative formate dehydrogenase; IMG reference gene:2505283785; PFAM: Cytochrome b(N-terminal)/b6/petB; TIGRFAM: formate dehydrogenase, gamma subunit.
     
  0.800
AEH45243.1
Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839:IPR004838:IPR001176; KEGG: tye:THEYE_A0342 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Aspartate aminotransferase; IMG reference gene:2505284692; PFAM: Aminotransferase class I and II.
     
  0.800
AEH45674.1
COGs: COG2864 Cytochrome b subunit of formate dehydrogenase; InterPro IPR006471; KEGG: nam:NAMH_1309 formate dehydrogenase subunit C; SPTR: Formate dehydrogenase subunit C; TIGRFAM: formate dehydrogenase, gamma subunit; IMG reference gene:2505285145; PFAM: Cytochrome b(N-terminal)/b6/petB; TIGRFAM: formate dehydrogenase, gamma subunit.
     
  0.800
AEH45675.1
Formate dehydrogenase subunit beta; COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterPro IPR017896:IPR017900; KEGG: ddf:DEFDS_1330 formate dehydrogenase subunit beta; SPTR: Formate dehydrogenase, beta subunit; IMG reference gene:2505285146; PFAM: 4Fe-4S binding domain.
     
  0.800
AEH45676.1
Nitrate reductase; COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; InterProIPR006311:IPR017909:IPR006655:IPR006963:IPR 006656:IPR006657; KEGG: ddf:DEFDS_1331 formate dehydrogenase subunit alpha; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; PRIAM: Nitrate reductase; SPTR: Formate dehydrogenase, alpha subunit; manually curated; selenocysteine-containing protein; IMG reference gene:2505285147; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxi [...]
     
  0.800
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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