Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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AEH44848.1Protein of unknown function DUF901; COGs: COG3688 RNA-binding protein containing a PIN domain; InterPro IPR010298; KEGG: sat:SYN_01764 putative cytoplasmic protein; PFAM: protein of unknown function DUF901; SPTR: Hypothetical cytosolic protein; IMG reference gene:2505284285; PFAM: Protein of unknown function (DUF901). (163 aa)    
Predicted Functional Partners:
AEH44851.1
COGs: COG0212 5-formyltetrahydrofolate cyclo-ligase; InterPro IPR002698; KEGG: tag:Tagg_1069 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase; SPTR: 5-formyltetrahydrofolate cyclo-ligase; IMG reference gene:2505284288; PFAM: 5-formyltetrahydrofolate cyclo-ligase family.
 
     0.807
AEH44850.1
Cobyrinic acid a,c-diamide synthase; COGs: COG1192 ATPase involved in chromosome partitioning; KEGG: ppd:Ppro_0583 cobyrinic acid a,c-diamide synthase; SPTR: Chromosome segregation ATPase; IMG reference gene:2505284287; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain.
  
    0.782
AEH44849.1
parB-like partition protein; COGs: COG1475 transcriptional regulator protein; InterPro IPR003115:IPR004437; KEGG: dak:DaAHT2_2007 ParB-like partition protein; PFAM: ParB domain protein nuclease; SMART: ParB domain protein nuclease; SPTR: Putative uncharacterized protein; TIGRFAM: parB-like partition protein; IMG reference gene:2505284286; PFAM: ParB-like nuclease domain; KorB domain; TIGRFAM: ParB-like partition proteins; Belongs to the ParB family.
  
    0.778
AEH44897.1
InterPro IPR013249:IPR014284; KEGG: oan:Oant_4467 FliA/WhiG family RNA polymerase sigma 28 subunit; PFAM: Sigma-70 region 4 type 2; SPTR: Putative RNA polymerase, sigma 28 subunit, FliA/WhiG family; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; IMG reference gene:2505284336; PFAM: Sigma-70, region 4; Sigma 54 modulation protein / S30EA ribosomal protein; TIGRFAM: RNA polymerase sigma factor, sigma-70 family.
 
    0.583
rlpA
Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.
       0.570
AEH43969.1
RNA methyltransferase, TrmH family, group 3; COGs: COG0566 rRNA methylase; InterPro IPR013123:IPR001537:IPR004441; KEGG: sth:STH3115 rRNA methyltransferase; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; SPTR: RNA methyltransferase, TrmH family, group 3; TIGRFAM: RNA methyltransferase, TrmH family, group 3; IMG reference gene:2505283366; PFAM: SpoU rRNA Methylase family; RNA 2'-O ribose methyltransferase substrate binding; TIGRFAM: rRNA methylase, putative, group 3; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RN [...]
  
    0.468
AEH45204.1
tRNA/rRNA methyltransferase (SpoU); COGs: COG0566 rRNA methylase; InterPro IPR001537; KEGG: rmr:Rmar_1290 tRNA/rRNA methyltransferase (SpoU); PFAM: tRNA/rRNA methyltransferase (SpoU); SPTR: tRNA/rRNA methyltransferase (SpoU); IMG reference gene:2505284651; PFAM: SpoU rRNA Methylase family.
  
    0.468
trmH
tRNA guanosine-2'-O-methyltransferase; Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
  
    0.468
cysS
Cysteine synthase; COGs: COG0215 Cysteinyl-tRNA synthetase; InterProIPR001926:IPR015803:IPR001216:IPR005856:IPR 002308; KEGG: sat:SYN_00075 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Cysteinyl-tRNA synthetase; TIGRFAM: cysteine synthase; cysteinyl-tRNA synthetase; IMG reference gene:2505283966; PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthases; cysteinyl-tRNA synthetase; cysteine synthase B.
  
    0.466
AEH44847.1
Sodium/hydrogen exchanger; COGs: COG4651 Kef-type K+ transport system predicted NAD-binding component; InterPro IPR006153:IPR003148; KEGG: dol:Dole_0855 sodium/hydrogen exchanger; PFAM: sodium/hydrogen exchanger; TrkA-N domain protein; SPTR: Sodium/hydrogen exchanger; IMG reference gene:2505284284; PFAM: TrkA-N domain; Sodium/hydrogen exchanger family; TIGRFAM: transporter, monovalent cation:proton antiporter-2 (CPA2) family.
       0.466
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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