close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH44869.1Cupin 2 conserved barrel domain protein; COGs: COG0662 Mannose-6-phosphate isomerase; InterPro IPR013096; KEGG: tye:THEYE_A1401 cupin domain protein; PFAM: Cupin 2 conserved barrel domain protein; SPTR: Cupin 2 conserved barrel domain protein; IMG reference gene:2505284306; PFAM: Cupin domain. (113 aa)    
Predicted Functional Partners:
AEH44593.1
Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR003362:IPR017472:IPR017475; KEGG: hya:HY04AAS1_0831 undecaprenyl-phosphate galactose phosphotransferase, WbaP; PFAM: sugar transferase; PRIAM: Undecaprenyl-phosphate galactose phosphotransferase; SPTR: Undecaprenyl-phosphate galactosephosphotransferase; TIGRFAM: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Undecaprenyl-phosphate galactose phosphotransferase, WbaP; IMG reference gene:2505284010; PFAM: Bacteri [...]
  
  
 0.790
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
 
     0.741
AEH44403.1
KEGG: dak:DaAHT2_0260 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505283815.
  
     0.727
hisI
Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
       0.705
AEH45633.1
KEGG: mtp:Mthe_0283 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505285103.
  
     0.647
AEH43988.1
COGs: COG1416 conserved hypothetical protein; KEGG: dsa:Desal_3394 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505283385; PFAM: DsrE/DsrF-like family.
  
     0.592
AEH44298.1
KEGG: nwa:Nwat_2662 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505283705.
  
     0.571
kdsB
3-deoxy-D-manno- octulosonatecytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
       0.566
AEH44188.1
InterPro IPR001623:IPR003095; KEGG: mhu:Mhun_0257 heat shock protein DnaJ-like; PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; SPTR: Heat shock protein DnaJ-like; IMG reference gene:2505283593; PFAM: DnaJ domain.
  
     0.555
AEH44536.1
Hypothetical protein; KEGG: sat:SYN_01357 putative cytoplasmic protein; SPTR: Hypothetical cytosolic protein; IMG reference gene:2505283951.
  
     0.497
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.