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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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AEH44880.1Cobalamin (vitamin B12) biosynthesis CbiM protein; COGs: COG0310 ABC-type Co2+ transport system permease component; InterPro IPR002751; KEGG: dsa:Desal_0774 cobalt transport protein CbiM; PFAM: cobalamin (vitamin B12) biosynthesis CbiM protein; SPTR: Cobalamin (Vitamin B12) biosynthesis CbiM protein; IMG reference gene:2505284318; PFAM: Cobalt uptake substrate-specific transmembrane region; TIGRFAM: cobalamin biosynthesis protein CbiM. (201 aa)    
Predicted Functional Partners:
AEH44879.1
Nickel transport complex, NikM subunit, transmembrane; COGs: COG5266 ABC-type Co2+ transport system periplasmic component; InterPro IPR019613; KEGG: ddf:DEFDS_0032 cobalt ABC transporter substrate-binding protein; PFAM: Nickel transport complex, NikM subunit, transmembrane; SPTR: Cobalt ABC transporter, substrate-binding protein; IMG reference gene:2505284317; PFAM: Nickel uptake substrate-specific transmembrane region.
  
 0.996
AEH44882.1
Cobalt ABC transporter, inner membrane subunit CbiQ; COGs: COG0619 ABC-type cobalt transport system permease component CbiQ and related transporter; InterPro IPR003339:IPR012809; KEGG: tye:THEYE_A1922 cobalt ABC transporter, permease protein CbiQ; PFAM: cobalt transport protein; SPTR: Cobalt ABC transporter, permease protein CbiQ; TIGRFAM: cobalt ABC transporter, inner membrane subunit CbiQ; IMG reference gene:2505284320; PFAM: Cobalt transport protein; TIGRFAM: cobalt ABC transporter, permease protein CbiQ.
 
 
 0.996
AEH44883.1
ABC transporter related protein; COGs: COG1122 ABC-type cobalt transport system ATPase component; InterPro IPR017871:IPR003593:IPR003439; KEGG: dsa:Desal_3208 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; IMG reference gene:2505284321; PFAM: ABC transporter.
 
 
 0.993
AEH44881.1
KEGG: aco:Amico_0065 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505284319.
    0.985
AEH45163.1
Nickel transport complex, NikM subunit, transmembrane; InterPro IPR019613; KEGG: ddf:DEFDS_0032 cobalt ABC transporter substrate-binding protein; PFAM: Nickel transport complex, NikM subunit, transmembrane; SPTR: Cobalt ABC transporter, substrate-binding protein; IMG reference gene:2505284610; PFAM: Nickel uptake substrate-specific transmembrane region.
 
  
 0.954
AEH45752.1
COGs: COG1010 Precorrin-3B methylase; InterPro IPR002750:IPR000878:IPR006363; KEGG: rrs:RoseRS_0572 precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiG protein; SPTR: Precorrin-3 methyltransferase / precorrin-2 dehydrogenase; TIGRFAM: precorrin-3B C17-methyltransferase; IMG reference gene:2505285228; PFAM: Cobalamin synthesis G C-terminus; Tetrapyrrole (Corrin/Porphyrin) Methylases; Cobalamin synthesis G N-terminal; TIGRFAM: precorrin-3B C17-methyltransferase.
 
  
 0.862
AEH45754.1
precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; COGs: COG2242 Precorrin-6B methylase 2; InterProIPR006365:IPR000878:IPR003358:IPR012818:IPR 014008; KEGG: dal:Dalk_0449 precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; methyltransferase; PRIAM: Precorrin-6Y C(5,15)-methyltransferase (decarboxylating); SPTR: Precorrin-6y C5,15-methyltransferase (Decarboxylating), CbiE subunit; TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; precorrin-6y C5,1 [...]
 
  
 0.668
AEH45854.1
COGs: COG0619 ABC-type cobalt transport system permease component CbiQ and related transporter; InterPro IPR003339; KEGG: dal:Dalk_4068 cobalt transport protein; PFAM: cobalt transport protein; SPTR: Cobalt transport protein; IMG reference gene:2505285337; PFAM: Cobalt transport protein.
  
  
 0.656
AEH43930.1
1-(5-phosphoribosyl)-5-amino-4-imidazole- carboxylate (AIR) carboxylase; COGs: COG1691 NCAIR mutase (PurE)-related protein; InterPro IPR000031; KEGG: dal:Dalk_0112 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; SPTR: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; IMG reference gene:2505283327; PFAM: AIR carboxylase.
  
    0.646
AEH45221.1
Asparagine synthase; COGs: COG1606 ATP-utilizing protein of the PP-loop superfamily; InterPro IPR005232:IPR001962; KEGG: ate:Athe_1202 PP-loop domain protein; PFAM: asparagine synthase; SPTR: PP-loop domain protein; IMG reference gene:2505284668; PFAM: Asparagine synthase; TIGRFAM: TIGR00268 family protein.
  
    0.619
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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