STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH44895.1COGs: COG1040 amidophosphoribosyltransferase; InterPro IPR000836; KEGG: cth:Cthe_2248 phosphoribosyltransferase; PFAM: phosphoribosyltransferase; SPTR: Phosphoribosyltransferase; IMG reference gene:2505284334; PFAM: Phosphoribosyl transferase domain; TIGRFAM: comF family protein. (221 aa)    
Predicted Functional Partners:
AEH45445.1
DNA protecting protein DprA; COGs: COG0758 Rossmann fold nucleotide-binding protein involved in DNA uptake; InterPro IPR003488; KEGG: gme:Gmet_0890 smf protein; PFAM: SMF family protein; SPTR: SMF protein; TIGRFAM: DNA protecting protein DprA; IMG reference gene:2505284906; PFAM: DNA recombination-mediator protein A; TIGRFAM: DNA protecting protein DprA.
 
 
 0.911
AEH44051.1
DNA internalization-related competence protein ComEC/Rec2; COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); InterPro IPR004477:IPR004797; KEGG: nwa:Nwat_0444 DNA internalization-like competence protein ComEC/Rec2; PFAM: ComEC/Rec2-related protein; SPTR: DNA internalization-related competence protein ComEC/Rec2; TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; ComEC/Rec2-related protein; IMG reference gene:2505283449; PFAM: Competence protein; Metallo-beta-lactamase superfamily; TIGRFAM: ComEC/Rec2-related protein; DNA internalization-related competence p [...]
 
  
 0.900
AEH44894.1
rfaE bifunctional protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
     
 0.858
AEH45149.1
Mg chelatase, subunit ChlI; COGs: COG0606 ATPase with chaperone activity; InterPro IPR004482:IPR003593:IPR000523:IPR001208; KEGG: dal:Dalk_5279 Mg chelatase, subunit ChlI; PFAM: magnesium chelatase ChlI subunit; SMART: AAA ATPase; SPTR: Mg chelatase, subunit ChlI; TIGRFAM: Mg chelatase, subunit ChlI; IMG reference gene:2505284596; PFAM: Magnesium chelatase, subunit ChlI; TIGRFAM: Mg chelatase-related protein.
 
  
 0.773
AEH44892.1
HAD-superfamily hydrolase, subfamily IA, variant 1; COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005833:IPR005834:IPR006402:IPR006439; KEGG: ana:alr4095 hypothetical protein; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: Alr4095 protein; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; HAD-superfamily hydrolase, subfamily IA, variant 3; IMG reference gene:2505284331; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfamily, subfa [...]
       0.768
AEH44893.1
InterPro IPR007197; KEGG: dtu:Dtur_0924 radical SAM domain protein; PFAM: Radical SAM domain protein; SPTR: Radical SAM domain protein; IMG reference gene:2505284332.
       0.762
AEH45765.1
COGs: COG2003 DNA repair protein; InterPro IPR020891:IPR001405; KEGG: dps:DP0715 DNA repair protein RadC; PFAM: DNA repair protein RadC; SPTR: Related to DNA repair protein RadC; TIGRFAM: DNA repair protein RadC; IMG reference gene:2505285241; PFAM: Protein of unknown function (DUF2466); TIGRFAM: DNA repair protein radc; Belongs to the UPF0758 family.
 
    0.736
AEH44523.1
Uncharacterized protein family UPF0102; COGs: COG0792 endonuclease distantly related to Holliday junction resolvase; InterPro IPR003509; KEGG: dak:DaAHT2_1166 protein of unknown function UPF0102; PFAM: Uncharacterised protein family UPF0102; SPTR: Putative uncharacterized protein; IMG reference gene:2505283938; PFAM: Uncharacterised protein family UPF0102; TIGRFAM: TIGR00252 family protein; Belongs to the UPF0102 family.
 
    0.700
AEH45665.1
COGs: COG1558 Flagellar basal body rod protein; InterPro IPR006299:IPR010930; KEGG: dak:DaAHT2_1190 flagellar basal-body rod protein FlgC; PFAM: protein of unknown function DUF1078 domain protein; SPTR: Flagellar basal-body rod protein FlgC; TIGRFAM: flagellar basal-body rod protein FlgC; IMG reference gene:2505285136; PFAM: Flagella basal body rod protein; Domain of unknown function (DUF1078); TIGRFAM: flagellar basal-body rod protein FlgC; Belongs to the flagella basal body rod proteins family.
   
   0.687
AEH44813.1
COGs: COG0287 Prephenate dehydrogenase; InterPro IPR004455:IPR003099; KEGG: dal:Dalk_1765 prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; NADP oxidoreductase coenzyme F420-dependent; SPTR: Prephenate dehydrogenase; IMG reference gene:2505284246; PFAM: Prephenate dehydrogenase.
   
  
 0.653
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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