close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH44898.1Protein of unknown function DUF147; COGs: COG1624 conserved hypothetical protein; InterPro IPR003390; KEGG: caa:Caka_1512 protein of unknown function DUF147; PFAM: protein of unknown function DUF147; SPTR: Putative uncharacterized protein; IMG reference gene:2505284337; PFAM: DisA bacterial checkpoint controller nucleotide-binding. (316 aa)    
Predicted Functional Partners:
AEH44899.1
Hypothetical protein; COGs: COG3359 exonuclease; KEGG: dal:Dalk_5288 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505284338.
 
     0.830
AEH44897.1
InterPro IPR013249:IPR014284; KEGG: oan:Oant_4467 FliA/WhiG family RNA polymerase sigma 28 subunit; PFAM: Sigma-70 region 4 type 2; SPTR: Putative RNA polymerase, sigma 28 subunit, FliA/WhiG family; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; IMG reference gene:2505284336; PFAM: Sigma-70, region 4; Sigma 54 modulation protein / S30EA ribosomal protein; TIGRFAM: RNA polymerase sigma factor, sigma-70 family.
       0.808
AEH44900.1
InterPro IPR000297; KEGG: cac:CA_C0279 peptidil-prolyl cis-trans isomerase; PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SPTR: PpiC-type peptidyl-prolyl cis-trans isomerase; IMG reference gene:2505284339; PFAM: PPIC-type PPIASE domain.
       0.791
AEH44896.1
Protease Do; COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR001478:IPR001940:IPR001254:IPR011782; KEGG: nhl:Nhal_1160 protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; PRIAM: HtrA2 peptidase; SMART: PDZ/DHR/GLGF domain protein; SPTR: Protease Do; TIGRFAM: protease Do; IMG reference gene:2505284335; PFAM: Trypsin; PDZ domain (Also known as DHR or GLGF); TIGRFAM: periplasmic serine protease, Do/DeqQ family; periplasmic serine pepetdase DegS.
       0.738
AEH43960.1
YbbR family protein; COGs: COG4856 conserved hypothetical protein; InterPro IPR012505; KEGG: ddf:DEFDS_1032 hypothetical protein; PFAM: YbbR family protein; SPTR: YbbR-like; IMG reference gene:2505283357; PFAM: YbbR-like protein.
  
  
 0.669
rex
CoA-binding domain protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
       0.529
glmM
Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
   
 
 0.528
AEH46013.1
Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; COGs: COG1109 Phosphomannomutase; InterProIPR005841:IPR005844:IPR005845:IPR005846:IPR 005843:IPR016066; KEGG: afw:Anae109_0166 phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; SPTR: Phosphomannomutase; IMG reference gene:2505285502; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosph [...]
   
 
 0.528
AEH44893.1
InterPro IPR007197; KEGG: dtu:Dtur_0924 radical SAM domain protein; PFAM: Radical SAM domain protein; SPTR: Radical SAM domain protein; IMG reference gene:2505284332.
 
     0.522
AEH44892.1
HAD-superfamily hydrolase, subfamily IA, variant 1; COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005833:IPR005834:IPR006402:IPR006439; KEGG: ana:alr4095 hypothetical protein; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: Alr4095 protein; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; HAD-superfamily hydrolase, subfamily IA, variant 3; IMG reference gene:2505284331; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfamily, subfa [...]
 
    0.485
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.