Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH44900.1InterPro IPR000297; KEGG: cac:CA_C0279 peptidil-prolyl cis-trans isomerase; PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SPTR: PpiC-type peptidyl-prolyl cis-trans isomerase; IMG reference gene:2505284339; PFAM: PPIC-type PPIASE domain. (287 aa)    
Predicted Functional Partners:
AEH44899.1
Hypothetical protein; COGs: COG3359 exonuclease; KEGG: dal:Dalk_5288 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505284338.
       0.818
AEH45662.1
Hypothetical protein; InterPro IPR019734:IPR013026; KEGG: dak:DaAHT2_1194 tetratricopeptide TPR_4; SPTR: Tetratricopeptide TPR_4; IMG reference gene:2505285133.
  
 
 0.804
AEH44896.1
Protease Do; COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR001478:IPR001940:IPR001254:IPR011782; KEGG: nhl:Nhal_1160 protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; PRIAM: HtrA2 peptidase; SMART: PDZ/DHR/GLGF domain protein; SPTR: Protease Do; TIGRFAM: protease Do; IMG reference gene:2505284335; PFAM: Trypsin; PDZ domain (Also known as DHR or GLGF); TIGRFAM: periplasmic serine protease, Do/DeqQ family; periplasmic serine pepetdase DegS.
     
 0.782
AEH44898.1
Protein of unknown function DUF147; COGs: COG1624 conserved hypothetical protein; InterPro IPR003390; KEGG: caa:Caka_1512 protein of unknown function DUF147; PFAM: protein of unknown function DUF147; SPTR: Putative uncharacterized protein; IMG reference gene:2505284337; PFAM: DisA bacterial checkpoint controller nucleotide-binding.
       0.782
AEH44897.1
InterPro IPR013249:IPR014284; KEGG: oan:Oant_4467 FliA/WhiG family RNA polymerase sigma 28 subunit; PFAM: Sigma-70 region 4 type 2; SPTR: Putative RNA polymerase, sigma 28 subunit, FliA/WhiG family; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; IMG reference gene:2505284336; PFAM: Sigma-70, region 4; Sigma 54 modulation protein / S30EA ribosomal protein; TIGRFAM: RNA polymerase sigma factor, sigma-70 family.
  
  
 0.770
rex
CoA-binding domain protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
  
    0.525
secF
Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
  
  
 0.518
AEH44484.1
COGs: COG4775 Outer membrane protein/protective antigen OMA87; InterPro IPR016474:IPR010827:IPR000184; KEGG: dak:DaAHT2_1309 outer membrane protein assembly complex, YaeT protein; PFAM: surface antigen (D15); surface antigen variable number repeat-containing protein; SPTR: Surface antigen (D15):Surface antigen variable number; TIGRFAM: outer membrane protein assembly complex, YaeT protein; IMG reference gene:2505283898; PFAM: Surface antigen variable number repeat; Surface antigen; TIGRFAM: outer membrane protein assembly complex, YaeT protein.
 
 
 0.470
obg
GTP-binding protein Obg/CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
     
 0.443
AEH44894.1
rfaE bifunctional protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
     
 0.440
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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