Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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AEH44908.1Peptidase U62 modulator of DNA gyrase; COGs: COG0312 Zn-dependent protease and their inactivated homologs; InterPro IPR002510; KEGG: tye:THEYE_A0931 protein TldD; PFAM: peptidase U62 modulator of DNA gyrase; SPTR: Protein TldD; IMG reference gene:2505284347; PFAM: Putative modulator of DNA gyrase. (460 aa)    
Predicted Functional Partners:
AEH44907.1
PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: fpl:Ferp_1052 PfkB domain protein; PFAM: PfkB domain protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505284346; PFAM: pfkB family carbohydrate kinase.
       0.799
AEH44906.1
KEGG: dvl:Dvul_2509 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505284345.
       0.773
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
       0.763
AEH44910.1
UbiD family decarboxylase; COGs: COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylase; InterPro IPR002830; KEGG: dma:DMR_21400 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; PFAM: Carboxylyase-related protein; SPTR: UbiD family decarboxylase; TIGRFAM: UbiD family decarboxylase; IMG reference gene:2505284349; PFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: menaquinone biosynthesis decarboxylase, SCO4490 family; UbiD family decarboxylases; Belongs to the UbiD family.
       0.754
AEH44905.1
Amidohydrolase; COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: dak:DaAHT2_0568 amidohydrolase; PFAM: amidohydrolase; SPTR: Amidohydrolase; IMG reference gene:2505284344; PFAM: Amidohydrolase family.
       0.586
mqnC
Radical SAM domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).
  
    0.583
obg
GTP-binding protein Obg/CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
       0.559
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
       0.559
rex
CoA-binding domain protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
       0.461
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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