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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
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[Homology]
Score
AEH44911.1COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR017900:IPR004089:IPR017896; KEGG: clj:CLJU_c20370 putative transcriptional regulator; PFAM: chemotaxis sensory transducer; SMART: chemotaxis sensory transducer; SPTR: Putative uncharacterized protein; IMG reference gene:2505284350; PFAM: Iron only hydrogenase large subunit, C-terminal domain; 4Fe-4S binding domain; Methyl-accepting chemotaxis protein (MCP) signaling domain. (616 aa)    
Predicted Functional Partners:
AEH44230.1
CheA signal transduction histidine kinase; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterProIPR008207:IPR004105:IPR003594:IPR002545:IPR 001789:IPR004358:IPR005467; KEGG: dps:DP2642 Che family two-component system sensory/regulatory protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; CheW domain protein; SMART: response regulator receiver; CheW domain protein; ATP-binding region ATPase domain protein; Hpt domain protein; SPTR: Two-component system sensory/r [...]
 
 0.959
AEH44228.1
CheW protein; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: dvm:DvMF_0284 CheW protein; PFAM: CheW domain protein; SMART: CheW domain protein; SPTR: CheW protein; IMG reference gene:2505283634; PFAM: CheW-like domain.
 
 
 0.904
cheB
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 
 0.769
AEH44231.1
MCP methyltransferase, CheR-type; COGs: COG1352 Methylase of chemotaxis methyl-accepting protein; InterPro IPR000780; KEGG: psl:Psta_3345 MCP methyltransferase, CheR-type; PFAM: MCP methyltransferase CheR-type; PRIAM: Protein-glutamate O-methyltransferase; SMART: MCP methyltransferase CheR-type; SPTR: MCP methyltransferase, CheR-type; IMG reference gene:2505283637; PFAM: CheR methyltransferase, SAM binding domain; CheR methyltransferase, all-alpha domain.
 
 
 0.764
AEH44948.1
Response regulator receiver sensor hybrid histidine kinase; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR020053:IPR001789:IPR003661:IPR003594:IPR 004358:IPR005467; KEGG: cts:Ctha_2310 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SPTR: Putative Histidine kinase; IMG reference gene:2505284387; PFAM: Histidine [...]
 
 
 0.738
AEH44379.1
InterPro IPR003149; KEGG: she:Shewmr4_3251 iron hydrogenase, small subunit; PFAM: iron hydrogenase small subunit; SPTR: Iron hydrogenase, small subunit; IMG reference gene:2505283786; PFAM: Iron hydrogenase small subunit.
 
 
 0.687
AEH46025.1
Formate dehydrogenase, alpha subunit; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterProIPR000759:IPR001041:IPR013027:IPR006963:IPR 006656:IPR006657:IPR018247:IPR017900:IPR006655:IPR017896:I PR006478; KEGG: dak:DaAHT2_0823 formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; ferredoxin; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; SPTR: Formate dehydrogenase, alpha subunit; TIGRFAM: formate dehydrogenase, alpha subunit; manually curated; selenocysteine- [...]
   
 
 0.659
AEH44381.1
Small GTP-binding protein; COGs: COG1160 GTPase; InterPro IPR005225:IPR002917:IPR001806:IPR003577; KEGG: pca:Pcar_1629 GTPases; PFAM: GTP-binding protein HSR1-related; SMART: Ras small GTPase, Ras type; SPTR: Predicted GTPases; TIGRFAM: small GTP-binding protein; IMG reference gene:2505283788; PFAM: GTPase of unknown function; TIGRFAM: hydrogenase maturation GTPase HydF; small GTP-binding protein domain.
 
     0.636
AEH45062.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001610:IPR003661:IPR003594:IPR 001789:IPR004358:IPR013656:IPR013767:IPR005467:IPR000700; KEGG: ppd:Ppro_0904 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; PAC repeat-containing protein; histidine kinase A domain protein; response regulator r [...]
 
 
 0.610
AEH46070.1
Hypothetical protein; InterPro IPR017900:IPR017896; KEGG: dap:Dacet_0088 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein; manually curated; IMG reference gene:2505285561; TIGRFAM: ferredoxin-type protein NapF; MauM/NapG family ferredoxin-type protein.
   
 
 0.596
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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