Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH44915.1Cell wall hydrolase/autolysin; COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002508; KEGG: ddf:DEFDS_0015 N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; SMART: cell wall hydrolase/autolysin; SPTR: N-acetylmuramoyl-L-alanine amidase; IMG reference gene:2505284354; PFAM: N-acetylmuramoyl-L-alanine amidase; Localisation of periplasmic protein complexes. (558 aa)    
Predicted Functional Partners:
AEH45994.1
Peptidase M23; COGs: COG4942 Membrane-bound metallopeptidase; InterPro IPR016047; KEGG: glo:Glov_1921 peptidase M23; PFAM: Peptidase M23; SPTR: Peptidase M23; IMG reference gene:2505285483; PFAM: Peptidase family M23.
 
   0.851
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
       0.809
AEH44670.1
COGs: COG2834 Outer membrane lipoprotein-sorting protein; InterPro IPR018323:IPR004564; KEGG: dak:DaAHT2_0277 outer membrane lipoprotein carrier protein LolA; PFAM: outer membrane lipoprotein carrier protein LolA; SPTR: Outer membrane lipoprotein carrier protein LolA; TIGRFAM: outer membrane lipoprotein carrier protein LolA; IMG reference gene:2505284089; PFAM: Outer membrane lipoprotein carrier protein LolA; TIGRFAM: periplasmic chaperone LolA.
  
 
   0.674
AEH44801.1
Lytic transglycosylase catalytic; InterPro IPR002482:IPR008258:IPR018392; KEGG: dal:Dalk_1929 lytic transglycosylase catalytic; PFAM: Lytic transglycosylase catalytic; Peptidoglycan-binding lysin domain; SPTR: Lytic transglycosylase catalytic; IMG reference gene:2505284233; PFAM: Transglycosylase SLT domain; LysM domain.
 
  
 0.629
AEH45405.1
KEGG: dba:Dbac_2225 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505284863; PFAM: Protein of unknown function (DUF1329).
    
   0.618
AEH44861.1
Competence/damage-inducible protein CinA; COGs: COG1546 Uncharacterized protein (competence- and mitomycin-induced); InterPro IPR001453:IPR008136:IPR008135; KEGG: dps:DP2957 competence-damage inducible protein (CinA); PFAM: CinA domain protein; molybdopterin binding domain; SPTR: CinA-like protein; TIGRFAM: competence/damage-inducible protein CinA; IMG reference gene:2505284298; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-terminal domain; molybden [...]
 
     0.566
nnrE
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
 
   
 0.530
AEH44663.1
Rhomboid family protein; COGs: COG0705 membrane protein; InterPro IPR002610; KEGG: ddf:DEFDS_0217 rhomboid family protein; PFAM: Rhomboid family protein; SPTR: Rhomboid family protein; IMG reference gene:2505284082; PFAM: Rhomboid family.
   
   0.525
AEH45424.1
Rhomboid family protein; COGs: COG0705 membrane protein; InterPro IPR002610; KEGG: ddf:DEFDS_0217 rhomboid family protein; PFAM: Rhomboid family protein; SPTR: Rhomboid family protein; IMG reference gene:2505284882; PFAM: Rhomboid family.
   
   0.525
AEH45925.1
Rhomboid family protein; InterPro IPR002610; KEGG: geo:Geob_1665 rhomboid family protein; PFAM: Rhomboid family protein; SPTR: Rhomboid family protein; IMG reference gene:2505285412; PFAM: Rhomboid family.
   
   0.525
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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