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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH44917.1Phage SPO1 DNA polymerase-related protein; COGs: COG1573 Uracil-DNA glycosylase; InterPro IPR005122:IPR005273; KEGG: rpf:Rpic12D_1308 phage SPO1 DNA polymerase-related protein; PFAM: Uracil-DNA glycosylase superfamily; SPTR: Putative uncharacterized protein; TIGRFAM: phage SPO1 DNA polymerase-related protein; IMG reference gene:2505284356; PFAM: Uracil DNA glycosylase superfamily; TIGRFAM: uracil-DNA glycosylase family domain; uracil-DNA glycosylase, family 4. (227 aa)    
Predicted Functional Partners:
AEH44919.1
Pyruvate carboxyltransferase; COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR002034:IPR000891; KEGG: dsa:Desal_0448 pyruvate carboxyltransferase; PFAM: pyruvate carboxyltransferase; SPTR: Pyruvate carboxyltransferase; IMG reference gene:2505284358; PFAM: HMGL-like; Belongs to the alpha-IPM synthase/homocitrate synthase family.
       0.627
AEH44918.1
Transcriptional regulator, NifA subfamily, Fis Family; COGs: COG3604 Transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains; InterProIPR002078:IPR003018:IPR003593:IPR020441:IPR 002197; KEGG: sfu:Sfum_1010 NifA subfamily transcriptional regulator; PFAM: sigma-54 factor interaction domain-containing protein; GAF domain protein; helix-turn-helix Fis-type; SMART: GAF domain protein; AAA ATPase; SPTR: Transcriptional regulator, NifA subfamily, Fis Family; IMG reference gene:2505284357; PFAM: GAF domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction [...]
       0.618
AEH44002.1
Peptidase M22 glycoprotease; COGs: COG1214 Inactive homolog of metal-dependent protease putative molecular chaperone; InterPro IPR000905; KEGG: dak:DaAHT2_0975 peptidase M22 glycoprotease; PFAM: peptidase M22 glycoprotease; SPTR: Peptidase M22 glycoprotease; IMG reference gene:2505283399; PFAM: Glycoprotease family; TIGRFAM: universal bacterial protein YeaZ.
  
    0.585
AEH45665.1
COGs: COG1558 Flagellar basal body rod protein; InterPro IPR006299:IPR010930; KEGG: dak:DaAHT2_1190 flagellar basal-body rod protein FlgC; PFAM: protein of unknown function DUF1078 domain protein; SPTR: Flagellar basal-body rod protein FlgC; TIGRFAM: flagellar basal-body rod protein FlgC; IMG reference gene:2505285136; PFAM: Flagella basal body rod protein; Domain of unknown function (DUF1078); TIGRFAM: flagellar basal-body rod protein FlgC; Belongs to the flagella basal body rod proteins family.
    
   0.538
AEH45544.1
Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
    
   0.520
AEH45805.1
Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
    
   0.520
AEH44051.1
DNA internalization-related competence protein ComEC/Rec2; COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); InterPro IPR004477:IPR004797; KEGG: nwa:Nwat_0444 DNA internalization-like competence protein ComEC/Rec2; PFAM: ComEC/Rec2-related protein; SPTR: DNA internalization-related competence protein ComEC/Rec2; TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; ComEC/Rec2-related protein; IMG reference gene:2505283449; PFAM: Competence protein; Metallo-beta-lactamase superfamily; TIGRFAM: ComEC/Rec2-related protein; DNA internalization-related competence p [...]
      
 0.487
AEH44801.1
Lytic transglycosylase catalytic; InterPro IPR002482:IPR008258:IPR018392; KEGG: dal:Dalk_1929 lytic transglycosylase catalytic; PFAM: Lytic transglycosylase catalytic; Peptidoglycan-binding lysin domain; SPTR: Lytic transglycosylase catalytic; IMG reference gene:2505284233; PFAM: Transglycosylase SLT domain; LysM domain.
   
   0.486
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
       0.456
AEH44915.1
Cell wall hydrolase/autolysin; COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002508; KEGG: ddf:DEFDS_0015 N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; SMART: cell wall hydrolase/autolysin; SPTR: N-acetylmuramoyl-L-alanine amidase; IMG reference gene:2505284354; PFAM: N-acetylmuramoyl-L-alanine amidase; Localisation of periplasmic protein complexes.
       0.403
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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