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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH44923.1Radical SAM domain protein; COGs: COG0535 Fe-S oxidoreductase; InterPro IPR007197; KEGG: rci:RCIX325 hypothetical protein; PFAM: Radical SAM domain protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505284362; PFAM: Radical SAM superfamily; TIGRFAM: nitrogenase cofactor biosynthesis protein NifB. (276 aa)    
Predicted Functional Partners:
AEH44925.1
Nitrogenase; COGs: COG2710 Nitrogenase molybdenum-iron protein alpha and beta chains; InterPro IPR000318:IPR000510; KEGG: dau:Daud_0147 nitrogenase; PFAM: oxidoreductase/nitrogenase component 1; PRIAM: Nitrogenase; SPTR: Nitrogenase; IMG reference gene:2505284364; PFAM: Nitrogenase component 1 type Oxidoreductase.
  
 0.963
AEH44924.1
COGs: COG2710 Nitrogenase molybdenum-iron protein alpha and beta chains; InterPro IPR000318:IPR000510:IPR005974:IPR010143; KEGG: dau:Daud_0146 nitrogenase component I, alpha chain; PFAM: oxidoreductase/nitrogenase component 1; SPTR: Nitrogenase protein alpha chain; TIGRFAM: nitrogenase component I, alpha chain; nitrogenase alpha chain; manually curated; selenocysteine-containing protein; IMG reference gene:2505284363; PFAM: Nitrogenase component 1 type Oxidoreductase; TIGRFAM: nitrogenase component I, alpha chain; nitrogenase alpha chain; Belongs to the NifD/NifK/NifE/NifN family.
 
  
 0.936
nifH
Nitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family.
 
  
 0.929
AEH44927.1
Oxidoreductase/nitrogenase component 1; COGs: COG2710 Nitrogenase molybdenum-iron protein alpha and beta chains; InterPro IPR000318:IPR000510; KEGG: mfs:MFS40622_0041 oxidoreductase/nitrogenase component 1; PFAM: oxidoreductase/nitrogenase component 1; SPTR: Oxidoreductase/nitrogenase component 1; IMG reference gene:2505284366; PFAM: Nitrogenase component 1 type Oxidoreductase; Belongs to the NifD/NifK/NifE/NifN family.
 
  
 0.895
AEH44922.1
COGs: COG0347 Nitrogen regulatory protein PII; InterPro IPR017918:IPR002187; KEGG: mba:Mbar_A2279 P-II family nitrogen regulatory protein; PFAM: nitrogen regulatory protein P-II; SPTR: Nitrogen regulatory protein P-II; IMG reference gene:2505284361; PFAM: Nitrogen regulatory protein P-II; Belongs to the P(II) protein family.
  
  
 0.771
AEH44921.1
COGs: COG0347 Nitrogen regulatory protein PII; InterPro IPR017918:IPR002187; KEGG: mfs:MFS40622_0032 nitrogen regulatory protein P-II; PFAM: nitrogen regulatory protein P-II; SPTR: Nitrogen regulatory protein P-II; IMG reference gene:2505284360; PFAM: Nitrogen regulatory protein P-II; Belongs to the P(II) protein family.
 
  
 0.761
cynS
Cyanate lyase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide; Belongs to the cyanase family.
       0.555
AEH44750.1
uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR000878:IPR003754:IPR003043:IPR006366; KEGG: dal:Dalk_4009 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; IMG reference gene:2505284177; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase.
  
  
 0.489
AEH44919.1
Pyruvate carboxyltransferase; COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR002034:IPR000891; KEGG: dsa:Desal_0448 pyruvate carboxyltransferase; PFAM: pyruvate carboxyltransferase; SPTR: Pyruvate carboxyltransferase; IMG reference gene:2505284358; PFAM: HMGL-like; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
  
 0.477
AEH44918.1
Transcriptional regulator, NifA subfamily, Fis Family; COGs: COG3604 Transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains; InterProIPR002078:IPR003018:IPR003593:IPR020441:IPR 002197; KEGG: sfu:Sfum_1010 NifA subfamily transcriptional regulator; PFAM: sigma-54 factor interaction domain-containing protein; GAF domain protein; helix-turn-helix Fis-type; SMART: GAF domain protein; AAA ATPase; SPTR: Transcriptional regulator, NifA subfamily, Fis Family; IMG reference gene:2505284357; PFAM: GAF domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction [...]
 
   
 0.469
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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