| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEH44750.1 | AEH44947.1 | Thein_0873 | Thein_1076 | uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR000878:IPR003754:IPR003043:IPR006366; KEGG: dal:Dalk_4009 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; IMG reference gene:2505284177; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | COGs: COG0755 ABC-type transport system involved in cytochrome c biogenesis permease component; InterPro IPR003557:IPR002541:IPR017562; KEGG: sfu:Sfum_0695 cytochrome c assembly protein; PFAM: cytochrome c assembly protein; SPTR: Probable cytochrome c biogenesis protein (CcsA); TIGRFAM: cytochrome c-type biogenesis protein CcsB; IMG reference gene:2505284386; PFAM: Cytochrome C assembly protein; TIGRFAM: cytochrome c-type biogenesis protein CcsB. | 0.875 |
| AEH44750.1 | AEH44948.1 | Thein_0873 | Thein_1077 | uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR000878:IPR003754:IPR003043:IPR006366; KEGG: dal:Dalk_4009 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; IMG reference gene:2505284177; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | Response regulator receiver sensor hybrid histidine kinase; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR020053:IPR001789:IPR003661:IPR003594:IPR 004358:IPR005467; KEGG: cts:Ctha_2310 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SPTR: Putative Histidine kinase; IMG reference gene:2505284387; PFAM: Histidine [...] | 0.532 |
| AEH44750.1 | AEH44949.1 | Thein_0873 | Thein_1078 | uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR000878:IPR003754:IPR003043:IPR006366; KEGG: dal:Dalk_4009 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; IMG reference gene:2505284177; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: hmo:HM1_3019 nitroreductase family protein; PFAM: nitroreductase; SPTR: Nitroreductase family protein; IMG reference gene:2505284388; PFAM: Nitroreductase family. | 0.446 |
| AEH44750.1 | AEH45449.1 | Thein_0873 | Thein_1589 | uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR000878:IPR003754:IPR003043:IPR006366; KEGG: dal:Dalk_4009 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; IMG reference gene:2505284177; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | Cytochrome c-type forming protein Ccs1; COGs: COG1333 ResB protein required for cytochrome c biosynthesis; KEGG: dps:DP1682 cytochrome c-type forming protein Ccs1; SPTR: Related to cytochrome c-type forming protein Ccs1; IMG reference gene:2505284910; PFAM: ResB-like family. | 0.762 |
| AEH44943.1 | AEH44944.1 | Thein_1072 | Thein_1073 | PAS/PAC sensor hybrid histidine kinase; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR000014:IPR003594:IPR001789:IPR004358:IPR 013767:IPR005467; KEGG: ddf:DEFDS_0784 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; response regulator receiver; SPTR: Putative uncharacterized protein; TIGRFAM: PAS sensor protein; IMG reference gene:2505284382; PFAM: Histidine kinase-, DNA gy [...] | COGs: COG0232 dGTP triphosphohydrolase; InterPro IPR003607:IPR006674:IPR006261; KEGG: dps:DP1797 deoxyguanosinetriphosphate triphosphohydrolase-like protein; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Related to deoxyguanosinetriphosphate triphosphohydrolase; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase; IMG reference gene:2505284383; PFAM: HD domain; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase, putative; Belongs to the dGTPase family. Type 2 subfamily. | 0.659 |
| AEH44943.1 | AEH44946.1 | Thein_1072 | Thein_1075 | PAS/PAC sensor hybrid histidine kinase; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR000014:IPR003594:IPR001789:IPR004358:IPR 013767:IPR005467; KEGG: ddf:DEFDS_0784 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; response regulator receiver; SPTR: Putative uncharacterized protein; TIGRFAM: PAS sensor protein; IMG reference gene:2505284382; PFAM: Histidine kinase-, DNA gy [...] | (Glutamate--ammonia-ligase) adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal tra [...] | 0.705 |
| AEH44943.1 | AEH44947.1 | Thein_1072 | Thein_1076 | PAS/PAC sensor hybrid histidine kinase; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR000014:IPR003594:IPR001789:IPR004358:IPR 013767:IPR005467; KEGG: ddf:DEFDS_0784 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; response regulator receiver; SPTR: Putative uncharacterized protein; TIGRFAM: PAS sensor protein; IMG reference gene:2505284382; PFAM: Histidine kinase-, DNA gy [...] | COGs: COG0755 ABC-type transport system involved in cytochrome c biogenesis permease component; InterPro IPR003557:IPR002541:IPR017562; KEGG: sfu:Sfum_0695 cytochrome c assembly protein; PFAM: cytochrome c assembly protein; SPTR: Probable cytochrome c biogenesis protein (CcsA); TIGRFAM: cytochrome c-type biogenesis protein CcsB; IMG reference gene:2505284386; PFAM: Cytochrome C assembly protein; TIGRFAM: cytochrome c-type biogenesis protein CcsB. | 0.638 |
| AEH44943.1 | AEH44948.1 | Thein_1072 | Thein_1077 | PAS/PAC sensor hybrid histidine kinase; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR000014:IPR003594:IPR001789:IPR004358:IPR 013767:IPR005467; KEGG: ddf:DEFDS_0784 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; response regulator receiver; SPTR: Putative uncharacterized protein; TIGRFAM: PAS sensor protein; IMG reference gene:2505284382; PFAM: Histidine kinase-, DNA gy [...] | Response regulator receiver sensor hybrid histidine kinase; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR020053:IPR001789:IPR003661:IPR003594:IPR 004358:IPR005467; KEGG: cts:Ctha_2310 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SPTR: Putative Histidine kinase; IMG reference gene:2505284387; PFAM: Histidine [...] | 0.998 |
| AEH44943.1 | AEH44949.1 | Thein_1072 | Thein_1078 | PAS/PAC sensor hybrid histidine kinase; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR000014:IPR003594:IPR001789:IPR004358:IPR 013767:IPR005467; KEGG: ddf:DEFDS_0784 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; response regulator receiver; SPTR: Putative uncharacterized protein; TIGRFAM: PAS sensor protein; IMG reference gene:2505284382; PFAM: Histidine kinase-, DNA gy [...] | COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: hmo:HM1_3019 nitroreductase family protein; PFAM: nitroreductase; SPTR: Nitroreductase family protein; IMG reference gene:2505284388; PFAM: Nitroreductase family. | 0.452 |
| AEH44943.1 | AEH44950.1 | Thein_1072 | Thein_1079 | PAS/PAC sensor hybrid histidine kinase; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR000014:IPR003594:IPR001789:IPR004358:IPR 013767:IPR005467; KEGG: ddf:DEFDS_0784 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; response regulator receiver; SPTR: Putative uncharacterized protein; TIGRFAM: PAS sensor protein; IMG reference gene:2505284382; PFAM: Histidine kinase-, DNA gy [...] | Inner-membrane translocator; COGs: COG0559 Branched-chain amino acid ABC-type transport system permease components; InterPro IPR001851; KEGG: dvm:DvMF_1483 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; IMG reference gene:2505284389; PFAM: Branched-chain amino acid transport system / permease component. | 0.406 |
| AEH44943.1 | AEH44951.1 | Thein_1072 | Thein_1080 | PAS/PAC sensor hybrid histidine kinase; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR000014:IPR003594:IPR001789:IPR004358:IPR 013767:IPR005467; KEGG: ddf:DEFDS_0784 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; response regulator receiver; SPTR: Putative uncharacterized protein; TIGRFAM: PAS sensor protein; IMG reference gene:2505284382; PFAM: Histidine kinase-, DNA gy [...] | Inner-membrane translocator; COGs: COG4177 ABC-type branched-chain amino acid transport system permease component; InterPro IPR001851; KEGG: sfu:Sfum_0384 ABC transporter related; PFAM: inner-membrane translocator; SPTR: ABC transporter related; IMG reference gene:2505284390; PFAM: Branched-chain amino acid transport system / permease component. | 0.406 |
| AEH44943.1 | queA | Thein_1072 | Thein_1074 | PAS/PAC sensor hybrid histidine kinase; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR000014:IPR003594:IPR001789:IPR004358:IPR 013767:IPR005467; KEGG: ddf:DEFDS_0784 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; response regulator receiver; SPTR: Putative uncharacterized protein; TIGRFAM: PAS sensor protein; IMG reference gene:2505284382; PFAM: Histidine kinase-, DNA gy [...] | S-adenosylmethionine/tRNA-ribosyltransferase- isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.703 |
| AEH44944.1 | AEH44943.1 | Thein_1073 | Thein_1072 | COGs: COG0232 dGTP triphosphohydrolase; InterPro IPR003607:IPR006674:IPR006261; KEGG: dps:DP1797 deoxyguanosinetriphosphate triphosphohydrolase-like protein; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Related to deoxyguanosinetriphosphate triphosphohydrolase; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase; IMG reference gene:2505284383; PFAM: HD domain; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase, putative; Belongs to the dGTPase family. Type 2 subfamily. | PAS/PAC sensor hybrid histidine kinase; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR000014:IPR003594:IPR001789:IPR004358:IPR 013767:IPR005467; KEGG: ddf:DEFDS_0784 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; response regulator receiver; SPTR: Putative uncharacterized protein; TIGRFAM: PAS sensor protein; IMG reference gene:2505284382; PFAM: Histidine kinase-, DNA gy [...] | 0.659 |
| AEH44944.1 | AEH44946.1 | Thein_1073 | Thein_1075 | COGs: COG0232 dGTP triphosphohydrolase; InterPro IPR003607:IPR006674:IPR006261; KEGG: dps:DP1797 deoxyguanosinetriphosphate triphosphohydrolase-like protein; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Related to deoxyguanosinetriphosphate triphosphohydrolase; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase; IMG reference gene:2505284383; PFAM: HD domain; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase, putative; Belongs to the dGTPase family. Type 2 subfamily. | (Glutamate--ammonia-ligase) adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal tra [...] | 0.788 |
| AEH44944.1 | AEH44947.1 | Thein_1073 | Thein_1076 | COGs: COG0232 dGTP triphosphohydrolase; InterPro IPR003607:IPR006674:IPR006261; KEGG: dps:DP1797 deoxyguanosinetriphosphate triphosphohydrolase-like protein; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Related to deoxyguanosinetriphosphate triphosphohydrolase; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase; IMG reference gene:2505284383; PFAM: HD domain; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase, putative; Belongs to the dGTPase family. Type 2 subfamily. | COGs: COG0755 ABC-type transport system involved in cytochrome c biogenesis permease component; InterPro IPR003557:IPR002541:IPR017562; KEGG: sfu:Sfum_0695 cytochrome c assembly protein; PFAM: cytochrome c assembly protein; SPTR: Probable cytochrome c biogenesis protein (CcsA); TIGRFAM: cytochrome c-type biogenesis protein CcsB; IMG reference gene:2505284386; PFAM: Cytochrome C assembly protein; TIGRFAM: cytochrome c-type biogenesis protein CcsB. | 0.788 |
| AEH44944.1 | AEH44948.1 | Thein_1073 | Thein_1077 | COGs: COG0232 dGTP triphosphohydrolase; InterPro IPR003607:IPR006674:IPR006261; KEGG: dps:DP1797 deoxyguanosinetriphosphate triphosphohydrolase-like protein; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Related to deoxyguanosinetriphosphate triphosphohydrolase; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase; IMG reference gene:2505284383; PFAM: HD domain; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase, putative; Belongs to the dGTPase family. Type 2 subfamily. | Response regulator receiver sensor hybrid histidine kinase; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR020053:IPR001789:IPR003661:IPR003594:IPR 004358:IPR005467; KEGG: cts:Ctha_2310 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SPTR: Putative Histidine kinase; IMG reference gene:2505284387; PFAM: Histidine [...] | 0.563 |
| AEH44944.1 | AEH44949.1 | Thein_1073 | Thein_1078 | COGs: COG0232 dGTP triphosphohydrolase; InterPro IPR003607:IPR006674:IPR006261; KEGG: dps:DP1797 deoxyguanosinetriphosphate triphosphohydrolase-like protein; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Related to deoxyguanosinetriphosphate triphosphohydrolase; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase; IMG reference gene:2505284383; PFAM: HD domain; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase, putative; Belongs to the dGTPase family. Type 2 subfamily. | COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: hmo:HM1_3019 nitroreductase family protein; PFAM: nitroreductase; SPTR: Nitroreductase family protein; IMG reference gene:2505284388; PFAM: Nitroreductase family. | 0.608 |
| AEH44944.1 | AEH44950.1 | Thein_1073 | Thein_1079 | COGs: COG0232 dGTP triphosphohydrolase; InterPro IPR003607:IPR006674:IPR006261; KEGG: dps:DP1797 deoxyguanosinetriphosphate triphosphohydrolase-like protein; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Related to deoxyguanosinetriphosphate triphosphohydrolase; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase; IMG reference gene:2505284383; PFAM: HD domain; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase, putative; Belongs to the dGTPase family. Type 2 subfamily. | Inner-membrane translocator; COGs: COG0559 Branched-chain amino acid ABC-type transport system permease components; InterPro IPR001851; KEGG: dvm:DvMF_1483 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; IMG reference gene:2505284389; PFAM: Branched-chain amino acid transport system / permease component. | 0.486 |
| AEH44944.1 | AEH44951.1 | Thein_1073 | Thein_1080 | COGs: COG0232 dGTP triphosphohydrolase; InterPro IPR003607:IPR006674:IPR006261; KEGG: dps:DP1797 deoxyguanosinetriphosphate triphosphohydrolase-like protein; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Related to deoxyguanosinetriphosphate triphosphohydrolase; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase; IMG reference gene:2505284383; PFAM: HD domain; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase, putative; Belongs to the dGTPase family. Type 2 subfamily. | Inner-membrane translocator; COGs: COG4177 ABC-type branched-chain amino acid transport system permease component; InterPro IPR001851; KEGG: sfu:Sfum_0384 ABC transporter related; PFAM: inner-membrane translocator; SPTR: ABC transporter related; IMG reference gene:2505284390; PFAM: Branched-chain amino acid transport system / permease component. | 0.486 |
| AEH44944.1 | queA | Thein_1073 | Thein_1074 | COGs: COG0232 dGTP triphosphohydrolase; InterPro IPR003607:IPR006674:IPR006261; KEGG: dps:DP1797 deoxyguanosinetriphosphate triphosphohydrolase-like protein; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Related to deoxyguanosinetriphosphate triphosphohydrolase; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase; IMG reference gene:2505284383; PFAM: HD domain; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase, putative; Belongs to the dGTPase family. Type 2 subfamily. | S-adenosylmethionine/tRNA-ribosyltransferase- isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.788 |