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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH44955.1Selenium metabolism protein YedF; InterPro IPR001455:IPR019870; KEGG: drm:Dred_1242 SirA family protein; PFAM: SirA-like domain-containing protein; SPTR: Transcriptional regulator; TIGRFAM: selenium metabolism protein YedF; IMG reference gene:2505284394; PFAM: DsrE/DsrF-like family; SirA-like protein; TIGRFAM: selenium metabolism protein YedF; Belongs to the sulfur carrier protein TusA family. (196 aa)    
Predicted Functional Partners:
AEH44956.1
Cysteine desulfurase family protein; COGs: COG0520 Selenocysteine lyase; InterPro IPR020578:IPR000192:IPR010969; KEGG: sat:SYN_01071 cysteine desulfurase / selenocysteine lyase; PFAM: aminotransferase class V; SPTR: Cysteine desulfurase / selenocysteine lyase; TIGRFAM: cysteine desulfurase family protein; IMG reference gene:2505284395; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurase family protein.
 
 
 
 0.909
AEH44957.1
KEGG: gsu:GSU0640 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505284396; PFAM: Protein of unknown function (DUF3343).
 
     0.821
selD
Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP.
 
   
 0.720
AEH45959.1
COGs: COG3276 Selenocysteine-specific translation elongation factor; InterProIPR000795:IPR005829:IPR004161:IPR015190:IPR 015191:IPR005225:IPR004535; KEGG: sfu:Sfum_1220 selenocysteine-specific translation elongation factor; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; Elongation factor SelB winged helix 2; Elongation factor SelB winged helix 3; PRIAM: Sulfate adenylyltransferase; SPTR: Selenocysteine-specific translation elongation factor SelB; TIGRFAM: selenocysteine-specific translation elongation factor; small GTP-binding protein; IMG reference [...]
 
   
 0.709
selA
L-seryl-tRNA selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
 
  
 0.698
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
       0.663
AEH43941.1
Hypothetical protein; InterPro IPR002119; KEGG: sfu:Sfum_3168 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505283338; PFAM: YeeE/YedE family (DUF395).
 
  
 0.633
AEH44753.1
COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR016454:IPR000192:IPR020578; KEGG: geo:Geob_2507 aminotransferase class V; PFAM: aminotransferase class V; PRIAM: Cysteine desulfurase; SPTR: Aminotransferase class V; IMG reference gene:2505284180; PFAM: Aminotransferase class-V.
   
 
 0.630
AEH44959.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR002355:IPR001763:IPR013027:IPR004099; KEGG: dps:DP2890 NADH oxidase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SMART: Rhodanese domain protein; SPTR: Related to NADH oxidase; IMG reference gene:2505284398; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Rhodanese-like domain; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain.
  
  
 0.608
AEH44952.1
COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: ank:AnaeK_1445 glycosyl transferase group 1; PFAM: glycosyl transferase group 1; SPTR: Glycosyl transferase group 1; IMG reference gene:2505284391; PFAM: Glycosyl transferases group 1.
       0.451
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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