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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
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[Homology]
Score
AEH44956.1Cysteine desulfurase family protein; COGs: COG0520 Selenocysteine lyase; InterPro IPR020578:IPR000192:IPR010969; KEGG: sat:SYN_01071 cysteine desulfurase / selenocysteine lyase; PFAM: aminotransferase class V; SPTR: Cysteine desulfurase / selenocysteine lyase; TIGRFAM: cysteine desulfurase family protein; IMG reference gene:2505284395; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurase family protein. (380 aa)    
Predicted Functional Partners:
AEH45113.1
SufBD protein; COGs: COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component; InterPro IPR000825; KEGG: dba:Dbac_1810 SufBD protein; PFAM: SufBD protein; SPTR: SufBD protein; IMG reference gene:2505284558; PFAM: Uncharacterized protein family (UPF0051).
 
 
 0.972
AEH45114.1
ABC transporter related protein; COGs: COG0396 ABC-type transport system involved in Fe-S cluster assembly ATPase component; InterPro IPR003593:IPR003439; KEGG: deg:DehalGT_0696 ABC transporter related protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Iron-regulated ABC transporter, atp-binding protein, SufC; IMG reference gene:2505284559; PFAM: ABC transporter; TIGRFAM: FeS assembly ATPase SufC.
 
  
 0.968
AEH44955.1
Selenium metabolism protein YedF; InterPro IPR001455:IPR019870; KEGG: drm:Dred_1242 SirA family protein; PFAM: SirA-like domain-containing protein; SPTR: Transcriptional regulator; TIGRFAM: selenium metabolism protein YedF; IMG reference gene:2505284394; PFAM: DsrE/DsrF-like family; SirA-like protein; TIGRFAM: selenium metabolism protein YedF; Belongs to the sulfur carrier protein TusA family.
 
 
 
 0.909
AEH44957.1
KEGG: gsu:GSU0640 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505284396; PFAM: Protein of unknown function (DUF3343).
 
   
 0.877
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
       0.686
cysS
Cysteine synthase; COGs: COG0215 Cysteinyl-tRNA synthetase; InterProIPR001926:IPR015803:IPR001216:IPR005856:IPR 002308; KEGG: sat:SYN_00075 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Cysteinyl-tRNA synthetase; TIGRFAM: cysteine synthase; cysteinyl-tRNA synthetase; IMG reference gene:2505283966; PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthases; cysteinyl-tRNA synthetase; cysteine synthase B.
  
  
 0.574
AEH44952.1
COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: ank:AnaeK_1445 glycosyl transferase group 1; PFAM: glycosyl transferase group 1; SPTR: Glycosyl transferase group 1; IMG reference gene:2505284391; PFAM: Glycosyl transferases group 1.
 
   
 0.536
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.453
AEH44953.1
COGs: COG0726 xylanase/chitin deacetylase; InterPro IPR002509; KEGG: bts:Btus_0502 polysaccharide deacetylase; PFAM: polysaccharide deacetylase; SPTR: Polysaccharide deacetylase; IMG reference gene:2505284392; PFAM: Polysaccharide deacetylase.
       0.451
AEH44954.1
Hypothetical protein; InterPro IPR005242; KEGG: geo:Geob_3377 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505284393; PFAM: Uncharacterised protein family (UPF0104); TIGRFAM: conserved hypothetical protein.
       0.451
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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