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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH44968.1Putative circadian clock protein, KaiC; COGs: COG0467 RecA-superfamily ATPase implicated in signal transduction; InterPro IPR014774:IPR010624; KEGG: aae:aq_204 hypothetical protein; PFAM: Circadian clock protein KaiC central region; SPTR: Putative uncharacterized protein; IMG reference gene:2505284407; PFAM: KaiC; TIGRFAM: KaiC domain protein, AF_0795 family. (294 aa)    
Predicted Functional Partners:
AEH45513.1
Bacterio-opsin activator HTH domain protein; COGs: COG1318 transcriptional regulator protein; KEGG: abi:Aboo_0950 bacterio-opsin activator HTH domain protein; SPTR: Bacterio-opsin activator HTH domain protein; IMG reference gene:2505284976; TIGRFAM: probable regulatory domain.
 
     0.799
AEH44967.1
Bifunctional GlmU protein; COGs: COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains); InterPro IPR001451; KEGG: dps:DP2923 bifunctional GlmU protein; SPTR: Probable bifunctional GlmU protein; IMG reference gene:2505284406.
       0.791
AEH44969.1
Nucleotidyl transferase; COGs: COG0448 ADP-glucose pyrophosphorylase; InterPro IPR005836:IPR018103:IPR005835; KEGG: dak:DaAHT2_1367 nucleotidyl transferase; PFAM: Nucleotidyl transferase; SPTR: Glucose-1-phosphate adenylyltransferase; IMG reference gene:2505284408; PFAM: Nucleotidyl transferase; TIGRFAM: glucose-1-phosphate adenylyltransferase; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
       0.779
rgy
Reverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
 
     0.772
bpsA
Protein of unknown function DUF43; Involved in the biosynthesis of branched-chain polyamines, which support the growth of thermophiles under high-temperature conditions. Catalyzes the sequential condensation of spermidine with the aminopropyl groups of decarboxylated S-adenosylmethionines to produce N(4)-bis(aminopropyl)spermidine via N(4)-aminopropylspermidine.
  
     0.722
AEH44144.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR004358:IPR013655:IPR003661:IPR003594:IPR 001789:IPR005467:IPR000014:IPR000700; KEGG: dak:DaAHT2_2564 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; histidine kinase A domain protein; response regulator receiver; SPTR: Multi-sensor hyb [...]
   
 
 0.684
AEH45521.1
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR004358:IPR003594:IPR001789:IPR005467; KEGG: cau:Caur_1383 PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; response regulator receiver; SPTR: PAS sensor protein; IMG reference gene:2505284984; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain.
   
 
 0.637
AEH45499.1
Protein of unknown function DUF72; COGs: COG1801 conserved hypothetical protein; InterPro IPR002763; KEGG: pho:PH0152 hypothetical protein; PFAM: protein of unknown function DUF72; SPTR: Putative uncharacterized protein PH0152; IMG reference gene:2505284961; PFAM: Protein of unknown function DUF72.
  
     0.626
AEH44655.1
COGs: COG1423 ATP-dependent DNA ligase homolog of eukaryotic ligase III; InterPro IPR012310:IPR001072; KEGG: tal:Thal_0814 ATP dependent DNA ligase; PFAM: ATP dependent DNA ligase; SPTR: Putative uncharacterized protein; IMG reference gene:2505284074; PFAM: ATP dependent DNA ligase domain; TIGRFAM: RNA ligase, Pab1020 family.
  
     0.609
AEH44680.1
ParB domain protein nuclease; InterPro IPR003115:IPR013838; KEGG: aae:aq_324 hypothetical protein; PFAM: ParB domain protein nuclease; SMART: ParB domain protein nuclease; SPTR: Putative uncharacterized protein; IMG reference gene:2505284099; PFAM: ParB-like nuclease domain.
  
     0.592
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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