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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH44971.1COGs: COG1237 Metal-dependent hydrolase of the beta-lactamase superfamily II; KEGG: nam:NAMH_1777 metal-dependent hydrolase of the beta-lactamase superfamily; SPTR: Putative uncharacterized protein; IMG reference gene:2505284410; PFAM: Metallo-beta-lactamase superfamily. (233 aa)    
Predicted Functional Partners:
AEH45510.1
Beta-lactamase domain-containing protein; COGs: COG1237 Metal-dependent hydrolase of the beta-lactamase superfamily II; KEGG: ppd:Ppro_1945 beta-lactamase domain-containing protein; SPTR: Beta-lactamase domain protein; IMG reference gene:2505284973; PFAM: Metallo-beta-lactamase superfamily.
  
  
 
0.928
AEH43962.1
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
     
 0.905
AEH44634.1
COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: ttj:TTHA1749 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (FolK); PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; SPTR:2-amino-4-hydroxy-6-hydroxymethyldihydropterid inepyrophosphokinase; TIGRFAM:2-amino-4-hydroxy-6-hydroxymethyldihydropte ridinepyrophosphokinase; manually curated; IMG reference gene:2505284053; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase.
     
  0.900
AEH44351.1
Ferredoxin (iron-sulfur cluster-binding protein); COGs: COG1149 MinD superfamily P-loop ATPase containing an inserted ferredoxin domain; InterPro IPR017896:IPR017900; KEGG: dat:HRM2_42450 ferredoxin (iron-sulfur cluster-binding protein); SPTR: Ferredoxin (Iron-sulfur cluster-binding protein); IMG reference gene:2505283758; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain.
 
     0.754
AEH44350.1
Cobyrinic acid ac-diamide synthase; COGs: COG1149 MinD superfamily P-loop ATPase containing an inserted ferredoxin domain; InterPro IPR017896:IPR017900; KEGG: dol:Dole_0576 cobyrinic acid ac-diamide synthase; SPTR: Cobyrinic acid ac-diamide synthase; IMG reference gene:2505283757; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain.
 
     0.747
AEH44349.1
Dinitrogenase iron-molybdenum cofactor biosynthesis protein; COGs: COG1433 conserved hypothetical protein; InterPro IPR003731; KEGG: dat:HRM2_46890 hypothetical protein; PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505283756; PFAM: Dinitrogenase iron-molybdenum cofactor.
 
     0.742
AEH44352.1
COGs: COG1433 conserved hypothetical protein; InterPro IPR003731; KEGG: tai:Taci_0393 dinitrogenase iron-molybdenum cofactor biosynthesis protein; PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis protein; SPTR: Dinitrogenase iron-molybdenum cofactor biosynthesis; IMG reference gene:2505283759; PFAM: Dinitrogenase iron-molybdenum cofactor.
 
     0.652
AEH44226.1
Protein of unknown function DUF89; COGs: COG1578 conserved hypothetical protein; InterPro IPR002791:IPR014444; KEGG: adg:Adeg_0546 protein of unknown function DUF89; PFAM: protein of unknown function DUF89; SPTR: Putative uncharacterized protein; IMG reference gene:2505283632; PFAM: Protein of unknown function DUF89.
 
     0.569
AEH44970.1
COGs: COG2930 conserved hypothetical protein; KEGG: dps:DP2816 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505284409; PFAM: Family of unknown function (DUF500).
       0.566
AEH44478.1
Radical SAM domain protein; COGs: COG0731 Fe-S oxidoreductase; InterPro IPR007197:IPR006638; KEGG: dak:DaAHT2_2249 radical SAM domain protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; IMG reference gene:2505283892; PFAM: Radical SAM superfamily.
 
     0.487
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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