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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH44982.1PHP domain protein; COGs: COG1796 DNA polymerase IV (family X); InterProIPR002054:IPR003583:IPR003141:IPR002008:IPR 004013; KEGG: adg:Adeg_1792 DNA-directed DNA polymerase; PFAM: PHP domain protein; SMART: DNA polymerase X; Helix-hairpin-helix DNA-binding class 1; phosphoesterase PHP domain protein; SPTR: DNA-directed DNA polymerase; IMG reference gene:2505284421; PFAM: PHP domain. (579 aa)    
Predicted Functional Partners:
AEH44929.1
COGs: COG0708 Exonuclease III; InterPro IPR005135:IPR000097:IPR004808; KEGG: gvi:glr0140 exodeoxyribonuclease III; PFAM: Endonuclease/exonuclease/phosphatase; PRIAM: Exodeoxyribonuclease III; SPTR: Exodeoxyribonuclease III; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; IMG reference gene:2505284368; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth).
   
 0.999
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 0.997
AEH45179.1
Histidinol-phosphate phosphatase family protein; COGs: COG0241 Histidinol phosphatase and related phosphatase; InterPro IPR006543:IPR006549:IPR005834; KEGG: nde:NIDE3031 bifunctional lipopolysaccharide heptosyltransferase II/D, D-heptose 1,7-bisphosphate phosphatase; PFAM: Haloacid dehalogenase domain protein hydrolase; PRIAM: Histidinol-phosphatase; SPTR: Putative uncharacterized protein; TIGRFAM: histidinol-phosphate phosphatase family protein; hydrolase, HAD-superfamily, subfamily IIIA; IMG reference gene:2505284626; PFAM: Polynucleotide kinase 3 phosphatase; TIGRFAM: HAD-superfamil [...]
    
 0.990
AEH44981.1
RNA methylase; COGs: COG1092 SAM-dependent methyltransferase; InterPro IPR000241:IPR002478; KEGG: chy:CHY_1437 hypothetical protein; PFAM: RNA methylase; SPTR: Putative uncharacterized protein; IMG reference gene:2505284420; PFAM: S-adenosylmethionine-dependent methyltransferase.
       0.828
AEH44980.1
Hypothetical protein; InterPro IPR011031; KEGG: sse:Ssed_4024 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505284419.
       0.820
AEH44979.1
COGs: COG1533 DNA repair photolyase; KEGG: dal:Dalk_0910 DNA repair photolyase-like protein; SPTR: DNA repair photolyase-like protein; IMG reference gene:2505284418.
       0.796
AEH44153.1
DNA ligase D, 3'-phosphoesterase domain protein; InterPro IPR014144; KEGG: nfa:nfa6770 ATP-dependent DNA ligase; SPTR: Putative ATP-dependent DNA ligase; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain protein; IMG reference gene:2505283554; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain.
  
 0.781
AEH45292.1
DNA polymerase LigD, ligase domain protein; COGs: COG1793 ATP-dependent DNA ligase; InterPro IPR014146:IPR012310:IPR012309:IPR016059; KEGG: mta:Moth_1488 ATP dependent DNA ligase, central; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; SPTR: ATP dependent DNA ligase, central; TIGRFAM: DNA polymerase LigD, ligase domain protein; IMG reference gene:2505284743; PFAM: ATP dependent DNA ligase domain; ATP dependent DNA ligase C terminal region; TIGRFAM: DNA polymerase LigD, ligase domain.
  
 0.781
AEH44983.1
Eight transmembrane protein EpsH; InterPro IPR019127:IPR013426; KEGG: dde:Dde_0847 hypothetical protein; PFAM: Exosortase EpsH-related; SPTR: Membrane protein, putative; TIGRFAM: eight transmembrane protein EpsH; IMG reference gene:2505284422; PFAM: Transmembrane exosortase (Exosortase_EpsH); TIGRFAM: eight transmembrane protein EpsH (proposed exosortase).
  
    0.780
AEH44984.1
EpsI family protein; InterPro IPR014263; KEGG: sus:Acid_6339 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: EpsI family protein; IMG reference gene:2505284423; PFAM: Protein of unknown function (DUF3485); TIGRFAM: EpsI family protein.
  
    0.780
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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