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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH44985.1DJ-1 family protein; COGs: COG0693 Putative intracellular protease/amidase; InterPro IPR002818:IPR006287; KEGG: tal:Thal_0984 DJ-1 family protein; PFAM: ThiJ/PfpI domain-containing protein; SPTR: DJ-1 family protein; TIGRFAM: DJ-1 family protein; IMG reference gene:2505284424; PFAM: DJ-1/PfpI family; TIGRFAM: DJ-1 family protein. (183 aa)    
Predicted Functional Partners:
AEH45586.1
Protein of unknown function DUF399; COGs: COG3016 Uncharacterized iron-regulated protein; InterPro IPR001478:IPR014782:IPR007314; KEGG: pmx:PERMA_0605 putative peptidase M1, membrane alanine aminopeptidase; PFAM: protein of unknown function DUF399; Peptidase M1 membrane alanine aminopeptidase; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: Putative peptidase M1, membrane alanine aminopeptidase; IMG reference gene:2505285053; PFAM: Protein of unknown function, DUF399; PDZ domain (Also known as DHR or GLGF).
  
 
 0.684
rpsJ
Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
   
   0.587
rplE
50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
   
   0.587
rpsS
Ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
   
   0.581
rplN
Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
    
   0.581
AEH44835.1
Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; COGs: COG0450 Peroxiredoxin; InterPro IPR000866:IPR019479:IPR017936; KEGG: dae:Dtox_2806 peroxiredoxin; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Peroxiredoxin-like; SPTR: Peroxiredoxin; manually curated; selenocysteine-containing protein; IMG reference gene:2505284269; PFAM: C-terminal domain of 1-Cys peroxiredoxin; AhpC/TSA family.
   
 
 0.564
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.549
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.543
rplM
Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
   0.539
rpmA
COGs: COG0211 Ribosomal protein L27; InterPro IPR001684:IPR018261; KEGG: pmx:PERMA_0052 50S ribosomal protein L27; PFAM: ribosomal protein L27; SPTR: 50S ribosomal protein L27; TIGRFAM: ribosomal protein L27; IMG reference gene:2505284188; PFAM: Ribosomal L27 protein; TIGRFAM: ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.
   
   0.525
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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