Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ureAUrease, gamma subunit; COGs: COG0831 Urea amidohydrolase (urease) gamma subunit; InterPro IPR012010:IPR002026; KEGG: tjr:TherJR_0605 urease, gamma subunit; PFAM: Urease gamma subunit region; PRIAM: Urease; SPTR: Urease subunit gamma; TIGRFAM: urease, gamma subunit; IMG reference gene:2505284450; PFAM: Urease, gamma subunit; TIGRFAM: urease, gamma subunit. (100 aa)    
Predicted Functional Partners:
ureC
Urease, alpha subunit; COGs: COG0804 Urea amidohydrolase (urease) alpha subunit; InterProIPR017950:IPR005848:IPR017952:IPR011612:IPR 006680:IPR017951; KEGG: tjr:TherJR_0607 urease, alpha subunit; PFAM: amidohydrolase; Urease alpha-subunit domain-containing protein; PRIAM: Urease; SPTR: Urease subunit alpha; TIGRFAM: urease, alpha subunit; IMG reference gene:2505284448; PFAM: Urease alpha-subunit, N-terminal domain; Amidohydrolase family; TIGRFAM: urease, alpha subunit.
 0.999
ureB
Urease, beta subunit; COGs: COG0832 Urea amidohydrolase (urease) beta subunit; InterPro IPR002019; KEGG: ant:Arnit_1070 urease subunit gamma; PFAM: Urease beta subunit; PRIAM: Urease; SPTR: Urease, gamma subunit; TIGRFAM: urease, beta subunit; IMG reference gene:2505284449; PFAM: Urease beta subunit; TIGRFAM: urease, beta subunit; Belongs to the urease beta subunit family.
 0.999
AEH45010.1
Transcriptional regulator, NifA subfamily, Fis Family; COGs: COG3604 Transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains; InterProIPR002078:IPR003018:IPR003593:IPR020441:IPR 002197; KEGG: aae:aq_218 NifA family transcriptional regulator; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; SMART: AAA ATPase; GAF domain protein; SPTR: Transcriptional regulator (NifA family); IMG reference gene:2505284451; PFAM: Bacterial regulatory protein, Fis family; Sigma-54 interaction domain.
       0.530
AEH44178.1
Hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR003495:IPR004392:IPR012202; KEGG: pmx:PERMA_0918 hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB; IMG reference gene:2505283583; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB.
 
  
 0.468
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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