Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH45022.1Thioredoxin; COGs: COG3118 Thioredoxin domain-containing protein; InterProIPR017937:IPR006662:IPR013766:IPR005746:IPR 017936; KEGG: dsa:Desal_1817 thioredoxin; PFAM: Thioredoxin domain-containing protein; SPTR: Thioredoxin; TIGRFAM: thioredoxin; IMG reference gene:2505284464; PFAM: Thioredoxin; TIGRFAM: thioredoxin; Belongs to the thioredoxin family. (107 aa)    
Predicted Functional Partners:
AEH45021.1
COGs: COG0492 Thioredoxin reductase; InterPro IPR008255:IPR000103:IPR013027:IPR005982; KEGG: tte:TTE2220 thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Thioredoxin reductase; TIGRFAM: thioredoxin reductase; IMG reference gene:2505284463; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase.
 
 0.987
AEH44241.1
Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 
 0.840
groL
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.818
AEH45097.1
COGs: COG0492 Thioredoxin reductase; InterPro IPR013027:IPR000103; KEGG: dak:DaAHT2_0308 FAD-dependent pyridine nucleotide-disulfide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Thioredoxin-disulfide reductase; IMG reference gene:2505284542; PFAM: Pyridine nucleotide-disulphide oxidoreductase.
 
 0.804
AEH45020.1
Outer membrane assembly lipoprotein YfiO; COGs: COG4105 DNA uptake lipoprotein; InterPro IPR017689:IPR013026; KEGG: dal:Dalk_2404 outer membrane assembly lipoprotein YfiO; SPTR: Outer membrane assembly lipoprotein YfiO; TIGRFAM: outer membrane assembly lipoprotein YfiO; IMG reference gene:2505284462; TIGRFAM: outer membrane assembly lipoprotein YfiO.
  
    0.803
AEH45049.1
Protein-tyrosine phosphatase, low molecular weight; COGs: COG0394 Protein-tyrosine-phosphatase; InterPro IPR017867; KEGG: adg:Adeg_1934 protein-tyrosine phosphatase, low molecular weight; PFAM: Protein-tyrosine phosphatase, low molecular weight; SMART: Protein-tyrosine phosphatase, low molecular weight; SPTR: Protein-tyrosine phosphatase, low molecular weight; IMG reference gene:2505284492; PFAM: Low molecular weight phosphotyrosine protein phosphatase.
  
 
 0.675
AEH44933.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0492 Thioredoxin reductase; InterPro IPR000103:IPR013027:IPR001327; KEGG: tye:THEYE_A0446 oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Oxidoreductase; IMG reference gene:2505284372; PFAM: Pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.618
AEH44959.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR002355:IPR001763:IPR013027:IPR004099; KEGG: dps:DP2890 NADH oxidase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SMART: Rhodanese domain protein; SPTR: Related to NADH oxidase; IMG reference gene:2505284398; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Rhodanese-like domain; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain.
     
 0.568
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
 
  
 0.550
hslV
20S proteasome A and B subunits; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
  
  
 0.497
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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