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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH45033.1COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: dak:DaAHT2_0557 nitroreductase; PFAM: nitroreductase; SPTR: Nitroreductase; IMG reference gene:2505284476; PFAM: Nitroreductase family. (175 aa)    
Predicted Functional Partners:
AEH45034.1
NADPH-dependent FMN reductase; COGs: COG0655 Multimeric flavodoxin WrbA; InterPro IPR005025; KEGG: iho:Igni_0620 NADPH-dependent FMN reductase; PFAM: NADPH-dependent FMN reductase; SPTR: NADPH-dependent FMN reductase; IMG reference gene:2505284477; PFAM: NADPH-dependent FMN reductase.
  
  
 0.831
speE-2
Spermine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine; Belongs to the spermidine/spermine synthase family.
       0.825
AEH45029.1
COGs: COG0685 5 10-methylenetetrahydrofolate reductase; InterPro IPR003171; KEGG: tjr:TherJR_2661 methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; SPTR: Methylenetetrahydrofolate reductase; IMG reference gene:2505284472; PFAM: Methylene-tetrahydrofolate reductase C terminal; Methylenetetrahydrofolate reductase.
       0.791
AEH45030.1
Two component, sigma54 specific, transcriptional regulator, Fis family; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterProIPR002078:IPR001789:IPR003593:IPR020441:IPR 002197; KEGG: sfu:Sfum_1934 two component, sigma54 specific, fis family transcriptional regulator; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase; SPTR: Two component, sigma54 specific, transcriptional regulator, Fis family; IMG reference gene:250 [...]
       0.791
AEH45031.1
COGs: COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation; InterProIPR003660:IPR000014:IPR003661:IPR003594:IPR 004358:IPR013767:IPR017232:IPR005467; KEGG: geo:Geob_2314 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; PAS domain containing protein; histidine kinase A domain protein; SPTR: PA [...]
       0.791
AEH45032.1
KEGG: dat:HRM2_11180 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505284475.
       0.791
AEH44414.1
Protein of unknown function DUF181; COGs: COG1944 conserved hypothetical protein; InterPro IPR003776:IPR001440:IPR019734:IPR013026; KEGG: dol:Dole_1241 hypothetical protein; PFAM: protein of unknown function DUF181; Tetratricopeptide TPR_1 repeat-containing protein; SMART: Tetratricopeptide repeat; SPTR: Putative uncharacterized protein; IMG reference gene:2505283826; PFAM: YcaO-like family; Tetratricopeptide repeat; TIGRFAM: uncharacterized domain.
 
  
 0.682
AEH45512.1
ABC-2 type transporter; InterPro IPR013526:IPR000412:IPR013525; KEGG: ppd:Ppro_1264 ABC-2 type transporter; PFAM: ABC-2 type transporter; SPTR: ABC-2 type transporter; IMG reference gene:2505284975; PFAM: ABC-2 type transporter; TIGRFAM: ABC-2 type transporter, NodJ family.
  
  
 0.588
AEH45752.1
COGs: COG1010 Precorrin-3B methylase; InterPro IPR002750:IPR000878:IPR006363; KEGG: rrs:RoseRS_0572 precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiG protein; SPTR: Precorrin-3 methyltransferase / precorrin-2 dehydrogenase; TIGRFAM: precorrin-3B C17-methyltransferase; IMG reference gene:2505285228; PFAM: Cobalamin synthesis G C-terminus; Tetrapyrrole (Corrin/Porphyrin) Methylases; Cobalamin synthesis G N-terminal; TIGRFAM: precorrin-3B C17-methyltransferase.
     
 0.547
AEH44959.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR002355:IPR001763:IPR013027:IPR004099; KEGG: dps:DP2890 NADH oxidase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SMART: Rhodanese domain protein; SPTR: Related to NADH oxidase; IMG reference gene:2505284398; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Rhodanese-like domain; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain.
     
 0.511
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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