Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH45042.1COGs: COG1925 Phosphotransferase system HPr-related protein; InterPro IPR001020:IPR005698:IPR000032; KEGG: mta:Moth_0015 HPrNtr; PFAM: phosphoryl transfer system HPr; SPTR: HPrNtr; TIGRFAM: phosphocarrier, HPr family; IMG reference gene:2505284485; PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family. (86 aa)    
Predicted Functional Partners:
AEH45043.1
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 0.999
AEH45272.1
COGs: COG2893 Phosphotransferase system mannose/fructose-specific component IIA; InterPro IPR004701; KEGG: dal:Dalk_1357 PTS system fructose subfamily IIA component; PFAM: PTS system fructose subfamily IIA component; SPTR: PTS system fructose subfamily IIA component; IMG reference gene:2505284721; PFAM: PTS system fructose IIA component; TIGRFAM: PTS system, mannose/fructose/sorbose family, IIA component.
 
 0.967
AEH45040.1
InterPro IPR013429; KEGG: sfu:Sfum_1903 FmdB family regulatory protein; PFAM: Putative regulatory protein FmdB; SPTR: Putative regulatory protein, FmdB family; TIGRFAM: regulatory protein, FmdB family; IMG reference gene:2505284483; PFAM: Zinc ribbon domain; TIGRFAM: putative regulatory protein, FmdB family.
       0.782
AEH45041.1
Nucleotidyl transferase; COGs: COG0448 ADP-glucose pyrophosphorylase; InterPro IPR005836:IPR005835; KEGG: dak:DaAHT2_1368 nucleotidyl transferase; PFAM: Nucleotidyl transferase; SPTR: Nucleotidyl transferase; IMG reference gene:2505284484; PFAM: Nucleotidyl transferase; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
       0.778
AEH45038.1
COGs: COG3876 conserved hypothetical protein; InterPro IPR008302; KEGG: dak:DaAHT2_0978 hypothetical protein; PFAM: Uncharacterised conserved protein UCP016719; SPTR: Putative uncharacterized protein; IMG reference gene:2505284481; PFAM: Protein of unknown function (DUF1343).
       0.736
AEH45039.1
Phosphoesterase RecJ domain protein; COGs: COG0618 Exopolyphosphatase-related protein; InterPro IPR001667; KEGG: dak:DaAHT2_1369 phosphoesterase RecJ domain protein; PFAM: phosphoesterase RecJ domain protein; SPTR: Phosphoesterase, RecJ-like:Phosphoesterase, DHHA1; IMG reference gene:2505284482; PFAM: DHH family.
       0.736
AEH45044.1
Lipopolysaccharide biosynthesis protein; InterPro IPR003856; KEGG: pmx:PERMA_0007 chain length determinant protein; PFAM: lipopolysaccharide biosynthesis protein; SPTR: Chain length determinant protein; IMG reference gene:2505284487.
       0.631
AEH45037.1
KEGG: pas:Pars_1241 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505284480.
       0.606
AEH45270.1
Putative PTS IIA-like nitrogen-regulatory protein PtsN; COGs: COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); InterPro IPR002178; KEGG: dat:HRM2_27890 PtsN2; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; SPTR: PtsN2; IMG reference gene:2505284719; PFAM: Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2.
 
  
 0.586
rpsG
Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
  
    0.562
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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