Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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AEH45069.1Phosphoglycerate mutase; COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR013078; KEGG: gur:Gura_4185 phosphoglycerate mutase; PFAM: Phosphoglycerate mutase; SPTR: Phosphoglycerate mutase; IMG reference gene:2505284513; PFAM: Phosphoglycerate mutase family. (210 aa)    
Predicted Functional Partners:
AEH45067.1
KEGG: tmt:Tmath_0891 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505284511; PFAM: Protein of unknown function (DUF1049).
       0.782
AEH45068.1
InterPro IPR005358; KEGG: dal:Dalk_2850 protein of unknown function UPF0153; PFAM: protein of unknown function UPF0153; SPTR: Putative uncharacterized protein; IMG reference gene:2505284512; PFAM: Uncharacterised protein family (UPF0153).
       0.782
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.723
AEH45752.1
COGs: COG1010 Precorrin-3B methylase; InterPro IPR002750:IPR000878:IPR006363; KEGG: rrs:RoseRS_0572 precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiG protein; SPTR: Precorrin-3 methyltransferase / precorrin-2 dehydrogenase; TIGRFAM: precorrin-3B C17-methyltransferase; IMG reference gene:2505285228; PFAM: Cobalamin synthesis G C-terminus; Tetrapyrrole (Corrin/Porphyrin) Methylases; Cobalamin synthesis G N-terminal; TIGRFAM: precorrin-3B C17-methyltransferase.
  
  
 0.683
AEH45298.1
Adenosylcobinamide-phosphateguanylyltransferase; COGs: COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase; InterPro IPR003203; KEGG: ddf:DEFDS_2051 adenosylcobinamide-phosphate guanylyltransferase; PFAM: cobalbumin biosynthesis protein; PRIAM: Adenosylcobinamide-phosphate guanylyltransferase; SPTR: Adenosylcobinamide-phosphate guanylyltransferase; IMG reference gene:2505284751; PFAM: Cobinamide kinase / cobinamide phosphate guanyltransferase.
 
  
 0.648
AEH45070.1
KEGG: ade:Adeh_3903 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505284514.
       0.615
cobS
Cobalamin-5-phosphate synthase CobS; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
  
 0.608
cobT
Nicotinate-nucleotide/dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
 
  
 0.603
AEH45066.1
COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR018483:IPR006224:IPR006145; KEGG: dtu:Dtur_0345 pseudouridine synthase; PFAM: pseudouridine synthase; SPTR: Pseudouridine synthase; IMG reference gene:2505284510; PFAM: RNA pseudouridylate synthase; TIGRFAM: pseudouridine synthase, RluA family.
       0.557
AEH45843.1
COGs: COG0825 Acetyl-CoA carboxylase alpha subunit; InterPro IPR000438:IPR013838:IPR020582; KEGG: dak:DaAHT2_0461 acetyl-CoA carboxylase; PFAM: Acetyl-CoA carboxylase, alpha subunit, conserved region; PRIAM: Acetyl-CoA carboxylase; SPTR: Acetyl-CoA carboxylase; IMG reference gene:2505285325; PFAM: Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit.
  
  
 0.530
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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