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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH45074.1Methyltransferase; COGs: COG0742 N6-adenine-specific methylase; InterPro IPR004398; KEGG: drm:Dred_2085 putative methyltransferase; PFAM: Conserved hypothetical protein CHP00095; SPTR: Putative uncharacterized protein; TIGRFAM: methyltransferase; IMG reference gene:2505284518; PFAM: Conserved hypothetical protein 95; TIGRFAM: RNA methyltransferase, RsmD family. (178 aa)    
Predicted Functional Partners:
coaD
Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
 
  
 0.946
AEH45076.1
KEGG: dak:DaAHT2_0614 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505284520; PFAM: Protein of unknown function (DUF3108).
 
     0.822
AEH45077.1
Class II aldolase/adducin family protein; COGs: COG0235 Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303; KEGG: tko:TK2132 L-fuculose phosphate aldolase; PFAM: class II aldolase/adducin family protein; SPTR: Fuculose-1-phosphate aldolase; IMG reference gene:2505284521; PFAM: Class II Aldolase and Adducin N-terminal domain; TIGRFAM: L-ribulose-5-phosphate 4-epimerase.
       0.787
AEH44514.1
Protein of unknown function DUF37; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.
  
    0.636
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
       0.605
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
       0.600
hrcA
Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.
       0.525
rnpA
Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
   
    0.497
AEH45067.1
KEGG: tmt:Tmath_0891 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505284511; PFAM: Protein of unknown function (DUF1049).
 
     0.439
rlmH
Protein of unknown function DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.
 
   
 0.403
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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