Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH45083.1COGs: COG2510 membrane protein; InterPro IPR000620; KEGG: cce:Ccel_0424 protein of unknown function DUF6 transmembrane; PFAM: protein of unknown function DUF6 transmembrane; SPTR: Putative uncharacterized protein; IMG reference gene:2505284528; PFAM: EamA-like transporter family. (142 aa)    
Predicted Functional Partners:
purD
Phosphoribosylamine/glycine ligase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR); Belongs to the GARS family.
       0.795
AEH44680.1
ParB domain protein nuclease; InterPro IPR003115:IPR013838; KEGG: aae:aq_324 hypothetical protein; PFAM: ParB domain protein nuclease; SMART: ParB domain protein nuclease; SPTR: Putative uncharacterized protein; IMG reference gene:2505284099; PFAM: ParB-like nuclease domain.
  
     0.582
AEH45081.1
Hypothetical protein; KEGG: tpr:Tpau_3474 crotonyl-CoA reductase; SPTR: Crotonyl-CoA reductase; IMG reference gene:2505284526.
       0.551
AEH44655.1
COGs: COG1423 ATP-dependent DNA ligase homolog of eukaryotic ligase III; InterPro IPR012310:IPR001072; KEGG: tal:Thal_0814 ATP dependent DNA ligase; PFAM: ATP dependent DNA ligase; SPTR: Putative uncharacterized protein; IMG reference gene:2505284074; PFAM: ATP dependent DNA ligase domain; TIGRFAM: RNA ligase, Pab1020 family.
  
     0.495
bpsA
Protein of unknown function DUF43; Involved in the biosynthesis of branched-chain polyamines, which support the growth of thermophiles under high-temperature conditions. Catalyzes the sequential condensation of spermidine with the aminopropyl groups of decarboxylated S-adenosylmethionines to produce N(4)-bis(aminopropyl)spermidine via N(4)-aminopropylspermidine.
  
     0.493
hisB
COGs: COG0131 Imidazoleglycerol-phosphate dehydratase; InterPro IPR010916:IPR020565:IPR000807; KEGG: cbh:CLC_1599 imidazoleglycerol-phosphate dehydratase; PFAM: imidazoleglycerol-phosphate dehydratase; PRIAM: Imidazoleglycerol-phosphate dehydratase; SPTR: Imidazoleglycerol-phosphate dehydratase; IMG reference gene:2505284525; PFAM: Imidazoleglycerol-phosphate dehydratase.
 
     0.485
AEH45152.1
tRNA pseudouridine synthase D TruD; COGs: COG0585 conserved hypothetical protein; InterPro IPR001656:IPR020119:IPR011760; KEGG: tye:THEYE_A0547 tRNA pseudouridine synthase D; PFAM: tRNA pseudouridine synthase D TruD; SPTR: tRNA pseudouridine synthase D; IMG reference gene:2505284599; PFAM: tRNA pseudouridine synthase D (TruD); TIGRFAM: tRNA pseudouridine synthase, TruD family.
  
     0.472
AEH45078.1
Nucleotide sugar dehydrogenase; COGs: COG1004 UDP-glucose 6-dehydrogenase; InterPro IPR001732:IPR014026:IPR014027:IPR017476; KEGG: ddf:DEFDS_0115 UDP-glucose 6-dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; PRIAM: UDP-glucose 6-dehydrogenase; SPTR: UDP-glucose 6-dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; IMG reference gene:2505284523; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP- [...]
       0.414
AEH45079.1
KEGG: sat:SYN_00762 hypothetical protein; SPTR: Hypothetical membrane protein; IMG reference gene:2505284524.
       0.414
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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