Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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Score
AEH45085.1NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR008089:IPR001509; KEGG: ckr:CKR_1837 hypothetical protein; PFAM: NAD-dependent epimerase/dehydratase; SPTR: Putative uncharacterized protein; IMG reference gene:2505284530; PFAM: NAD dependent epimerase/dehydratase family. (319 aa)    
Predicted Functional Partners:
AEH45078.1
Nucleotide sugar dehydrogenase; COGs: COG1004 UDP-glucose 6-dehydrogenase; InterPro IPR001732:IPR014026:IPR014027:IPR017476; KEGG: ddf:DEFDS_0115 UDP-glucose 6-dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; PRIAM: UDP-glucose 6-dehydrogenase; SPTR: UDP-glucose 6-dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; IMG reference gene:2505284523; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP- [...]
 0.974
AEH45087.1
Sugar transferase, PEP-CTERM system associated; COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR017475:IPR017464:IPR003362; KEGG: dat:HRM2_19690 CpsE; PFAM: sugar transferase; SPTR: CpsE; TIGRFAM: sugar transferase, PEP-CTERM system associated; exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; IMG reference gene:2505284532; PFAM: Bacterial sugar transferase; TIGRFAM: sugar transferase, PEP-CTERM system associated; exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase.
 
  
 0.841
glmS
Glucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
 
 0.820
AEH45988.1
UTP-glucose-1-phosphate uridylyltransferase; COGs: COG1210 UDP-glucose pyrophosphorylase; InterPro IPR005835:IPR005771; KEGG: dak:DaAHT2_0367 UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase; PRIAM: UTP--glucose-1-phosphate uridylyltransferase; SPTR: UTP-glucose-1-phosphate uridylyltransferase; TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; IMG reference gene:2505285477; PFAM: Nucleotidyl transferase; TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase.
  
 
 0.819
AEH44475.1
COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: sfu:Sfum_2348 glycosyl transferase, group 1; PFAM: glycosyl transferase group 1; SPTR: Glycosyl transferase, group 1; IMG reference gene:2505283889; PFAM: Glycosyl transferases group 1.
   
 
  0.803
AEH44473.1
Alpha,alpha-trehalose-phosphate synthase (UDP-forming); COGs: COG0380 Trehalose-6-phosphate synthase; InterPro IPR012766:IPR003337:IPR006379:IPR001830; KEGG: mem:Memar_2216 putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; PFAM: glycosyl transferase family 20; trehalose-phosphatase; SPTR: Alpha,alpha-trehalose-phosphate synthase (UDP-forming); TIGRFAM: alpha,alpha-trehalose-phosphate synthase [UDP-forming]; trehalose-phosphatase; HAD-superfamily hydrolase, subfamily IIB; IMG reference gene:2505283887; PFAM: Trehalose-phosphatase; Glycosyltransferase fami [...]
     
 0.801
AEH45088.1
COGs: COG0489 ATPase involved in chromosome partitioning; KEGG: dat:HRM2_19680 putative exopolysaccharide biosynthesis protein (protein-tyrosine kinase); SPTR: Putative exopolysaccharide biosynthesis protein (Protein-tyrosine kinase); IMG reference gene:2505284533.
  
  
 0.781
AEH45090.1
Polysaccharide chain length determinant protein, PEP-CTERM locus subfamily; COGs: COG3206 Uncharacterized protein involved in exopolysaccharide biosynthesis; InterPro IPR014345:IPR003856; KEGG: dat:HRM2_19670 GumC1; PFAM: lipopolysaccharide biosynthesis protein; SPTR: GumC1; TIGRFAM: polysaccharide chain length determinant protein, PEP-CTERM locus subfamily; IMG reference gene:2505284535; PFAM: Chain length determinant protein; TIGRFAM: polysaccharide chain length determinant protein, PEP-CTERM locus subfamily.
  
  
 0.768
AEH45084.1
KEGG: dps:DP3093 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505284529.
       0.766
AEH45092.1
Polysaccharide export protein; COGs: COG1596 Periplasmic protein involved in polysaccharide export; InterPro IPR003715:IPR019554; KEGG: dat:HRM2_19700 periplasmic polysaccharide export protein; PFAM: polysaccharide export protein; Soluble ligand binding domain; SPTR: Periplasmic polysaccharide export protein; IMG reference gene:2505284537; PFAM: Polysaccharide biosynthesis/export protein; SLBB domain; TIGRFAM: putative polysaccharide export protein, PEP-CTERM sytem-associated.
  
  
 0.753
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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