STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEH45105.1Helix-turn-helix domain protein; InterPro IPR001387:IPR013096; KEGG: amc:MADE_03313 transcriptional regulator, Cro/CI family protein; PFAM: helix-turn-helix domain protein; Cupin 2 conserved barrel domain protein; SMART: helix-turn-helix domain protein; SPTR: Transcriptional regulator, Cro/CI family protein; IMG reference gene:2505284550; PFAM: Helix-turn-helix. (182 aa)    
Predicted Functional Partners:
AEH45104.1
AzlC family protein; COGs: COG1296 branched-chain amino acid permease (azaleucine resistance); InterPro IPR011606; KEGG: ttj:TTHA0235 hypothetical protein; PFAM: AzlC family protein; SPTR: Transporter; IMG reference gene:2505284549; PFAM: AzlC protein; TIGRFAM: 4-azaleucine resistance probable transporter AzlC.
 
     0.805
AEH45103.1
Branched-chain amino acid transport; InterPro IPR008407; KEGG: mja:MJ1155.1 hypothetical protein; PFAM: branched-chain amino acid transport; SPTR: Uncharacterized protein MJ1155.1; IMG reference gene:2505284548; PFAM: Branched-chain amino acid transport protein (AzlD).
       0.773
AEH45728.1
Cupin 2 conserved barrel domain protein; InterPro IPR001387:IPR013096; KEGG: gur:Gura_0980 XRE family transcriptional regulator; PFAM: Cupin 2 conserved barrel domain protein; helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: Transcriptional regulator, XRE family; IMG reference gene:2505285202; PFAM: Cupin domain; Helix-turn-helix.
  
  
 0.657
recR
Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
  
    0.570
dnaX
DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
    0.569
AEH45101.1
Uncharacterized protein family UPF0133; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
  
    0.565
AEH45106.1
Anaerobic ribonucleoside-triphosphate reductase activating protein; COGs: COG1180 Pyruvate-formate lyase-activating enzyme; InterPro IPR012840:IPR007197:IPR001989; KEGG: hth:HTH_1738 pyruvate formate-lyase activating enzyme; PFAM: Radical SAM domain protein; SPTR: Pyruvate formate-lyase activating enzyme; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase activating protein; IMG reference gene:2505284551; PFAM: Radical SAM superfamily; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase activating protein.
       0.534
AEH45107.1
Peptidase M48 Ste24p; COGs: COG4783 Putative Zn-dependent protease contains TPR repeats; InterPro IPR001915; KEGG: wsu:WS1322 hypothetical protein; PFAM: peptidase M48 Ste24p; SPTR: Peptidase M48, Ste24p; IMG reference gene:2505284552; PFAM: Peptidase family M48.
       0.534
ffh
Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
  
    0.440
AEH45096.1
COGs: COG0491 Zn-dependent hydrolase including glyoxylase; KEGG: dak:DaAHT2_0323 hydroxyacylglutathione hydrolase; SPTR: Beta-lactamase-like; IMG reference gene:2505284541; PFAM: Metallo-beta-lactamase superfamily.
  
    0.431
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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