Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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AEH45106.1Anaerobic ribonucleoside-triphosphate reductase activating protein; COGs: COG1180 Pyruvate-formate lyase-activating enzyme; InterPro IPR012840:IPR007197:IPR001989; KEGG: hth:HTH_1738 pyruvate formate-lyase activating enzyme; PFAM: Radical SAM domain protein; SPTR: Pyruvate formate-lyase activating enzyme; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase activating protein; IMG reference gene:2505284551; PFAM: Radical SAM superfamily; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase activating protein. (231 aa)    
Predicted Functional Partners:
AEH44009.1
COGs: COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase; InterPro IPR005144:IPR012833; KEGG: ate:Athe_0548 anaerobic ribonucleoside triphosphate reductase; PFAM: ATP-cone domain protein; SPTR: Anaerobic ribonucleoside-triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; IMG reference gene:2505283407; PFAM: ATP cone domain; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase.
  
 0.976
AEH45107.1
Peptidase M48 Ste24p; COGs: COG4783 Putative Zn-dependent protease contains TPR repeats; InterPro IPR001915; KEGG: wsu:WS1322 hypothetical protein; PFAM: peptidase M48 Ste24p; SPTR: Peptidase M48, Ste24p; IMG reference gene:2505284552; PFAM: Peptidase family M48.
       0.778
AEH44008.1
Hypothetical protein; KEGG: pmo:Pmob_0978 anaerobic ribonucleoside triphosphate reductase; SPTR: Anaerobic ribonucleoside-triphosphate reductase, putative; IMG reference gene:2505283406.
 
  
 0.765
ffh
Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
       0.618
AEH45103.1
Branched-chain amino acid transport; InterPro IPR008407; KEGG: mja:MJ1155.1 hypothetical protein; PFAM: branched-chain amino acid transport; SPTR: Uncharacterized protein MJ1155.1; IMG reference gene:2505284548; PFAM: Branched-chain amino acid transport protein (AzlD).
       0.534
AEH45104.1
AzlC family protein; COGs: COG1296 branched-chain amino acid permease (azaleucine resistance); InterPro IPR011606; KEGG: ttj:TTHA0235 hypothetical protein; PFAM: AzlC family protein; SPTR: Transporter; IMG reference gene:2505284549; PFAM: AzlC protein; TIGRFAM: 4-azaleucine resistance probable transporter AzlC.
       0.534
AEH45105.1
Helix-turn-helix domain protein; InterPro IPR001387:IPR013096; KEGG: amc:MADE_03313 transcriptional regulator, Cro/CI family protein; PFAM: helix-turn-helix domain protein; Cupin 2 conserved barrel domain protein; SMART: helix-turn-helix domain protein; SPTR: Transcriptional regulator, Cro/CI family protein; IMG reference gene:2505284550; PFAM: Helix-turn-helix.
       0.534
rpsP
COGs: COG0228 Ribosomal protein S16; InterPro IPR000307; KEGG: csc:Csac_2157 30S ribosomal protein S16; PFAM: ribosomal protein S16; SPTR: 30S ribosomal protein S16; TIGRFAM: ribosomal protein S16; IMG reference gene:2505284554; PFAM: Ribosomal protein S16; TIGRFAM: ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
       0.523
AEH45101.1
Uncharacterized protein family UPF0133; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
       0.416
rimM
16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.
  
    0.407
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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